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Gene ontology
Version 2014-12-22
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Details for tryptophan 2,3-dioxygenase activity
1.13.11.11
Gene ontology ID
GO:0004833
Definition
Catalysis of the reaction: L-tryptophan + O2 = N-formyl-L-kynurenine
Synonyms
1. indolamine 2,3-dioxygenase activity
2. indoleamine-pyrrole 2,3-dioxygenase activity
3. L-tryptophan 2,3-dioxygenase activity
4. L-tryptophan pyrrolase activity
5. L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing)
6. TDO
7. tryptamin 2,3-dioxygenase activity
8. tryptamine 2,3-dioxygenase activity
9. tryptophan oxygenase activity
10. tryptophan peroxidase activity
11. tryptophan pyrrolase activity
References
1. EC 1.13.11.11
2. MetaCyc TRYPTOPHAN-23-DIOXYGENASE-RXN
3. Reactome: R-HSA-198563 "IDO1 dioxygenates L-Trp to NFK"
4. Reactome: R-HSA-71188 "TDO tetramer dioxygenates L-Trp to NFK"
5. Reactome: R-HSA-888614 "IDO2 dioxygenates L-Trp to NFK"
6. RHEA: 24536
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