2.7.1.67Gene ontology ID
GO:0004430
Definition
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = 1-phosphatidyl-1D-myo-inositol 4-phosphate + ADP + 2 H(+)
Synonyms
1. ATP:1-phosphatidyl-1D-myo-inositol 4-phosphotransferase activity
2. phosphatidylinositol 4-kinase activity
3. phosphatidylinositol kinase (phosphorylating) activity
4. phosphatidylinositol kinase activity
5. PI 4-kinase activity
6. PI kinase activity
7. PI4-kinase activity
8. PI4K
9. PI4K-alpha activity
10. PtdIns-4-kinase activity
11. type II phosphatidylinositol kinase activity
References
1. EC 2.7.1.672. RHEA: 19877
3. KEGG REACTION: R03361
4. MetaCyc 1-PHOSPHATIDYLINOSITOL-KINASE-RXN5. Reactome: R-HSA-1675780 "PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane"
6. Reactome: R-HSA-1675813 "PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane"
7. Reactome: R-HSA-1675883 "PI is phosphorylated to PI4P by PI4KB at the Golgi membrane"
8. Reactome: R-HSA-1675974 "PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane"
9. Reactome: R-HSA-1676185 "PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane"
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at least 1 tissue/ enzyme/ localization link in this branch
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tissue/ enzyme/ localization link to BRENDA