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Gene ontology
Version 2014-12-22
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Details for gamma-glutamylcyclotransferase activity
4.3.2.9
Gene ontology ID
GO:0003839
Definition
Catalysis of the reaction: (5-L-glutamyl)-L-amino acid = 5-oxoproline + L-amino acid
Synonyms
1. (5-L-glutamyl)-L-amino-acid 5-glutamyltransferase (cyclizing)
2. gamma-glutamyl-amino acid cyclotransferase activity
3. gamma-L-glutamylcyclotransferase activity
4. L-glutamic cyclase activity
References
1. PMID 18515354
2. EC 4.3.2.9
3. MetaCyc GAMMA-GLUTAMYLCYCLOTRANSFERASE-RXN
4. Reactome: R-HSA-1247922 "GGCT transforms gGluCys to OPRO"
5. Reactome: R-HSA-6785928 "CHAC1,2 cleaves GSH to OPRO and CysGly"
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
molecular_function is a
catalytic activity is a
lyase activity is a
carbon-nitrogen lyase activity is a
amidine-lyase activity is a
gamma-glutamylcyclotransferase activity is a
Tree view
Gene ontology
biological_process is a
cellular_component is a
molecular_function is a
binding is a
catalytic activity is a
catalytic activity, acting on a protein is a
catalytic activity, acting on DNA is a
catalytic activity, acting on RNA is a
cyclase activity is a
hydrolase activity is a
isomerase activity is a
ligase activity is a
lyase activity is a
2-amino-5-formylamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one formate-lyase activity is a
alkylmercury lyase activity is a
carbon phosphorus lyase activity is a
carbon-carbon lyase activity is a
carbon-halide lyase activity is a
carbon-nitrogen lyase activity is a
amidine-lyase activity is a
(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity is a
argininosuccinate lyase activity is a
gamma-glutamylaminecyclotransferase activity is a
gamma-glutamylcyclotransferase activity is a
glutathione specific gamma-glutamylcyclotransferase activity is a
N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity is a
ureidoglycolate lyase activity is a
amine-lyase activity is a
ammonia-lyase activity is a
cyanate hydratase activity is a
carbon-oxygen lyase activity is a
carbon-sulfur lyase activity is a
cobalt-precorrin-5A acetaldehyde-lyase activity is a
ferrochelatase activity is a
indoleacetaldoxime dehydratase activity is a
phosphorus-oxygen lyase activity is a
sirohydrochlorin cobaltochelatase activity is a
peptidoglycan muralytic activity is a
transferase activity is a
molecular transducer activity is a
nutrient reservoir activity is a
protein tag is a
small molecule sensor activity is a
structural molecule activity is a
transcription regulator activity is a
transporter activity is a