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Ontology explorer

Gene ontology
Version 2014-12-22
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Details for chondroitin B lyase activity
4.2.2.19
Gene ontology ID
GO:0033999
Definition
Catalysis of the reaction: dermatan sulfate = n 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate. This reaction is the eliminative cleavage of dermatan sulfate containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucurosonyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups to yield a 4,5-unsaturated dermatan-sulfate disaccharide (DeltaUA-GalNAC-4S). Chondroitin sulfate B is also known as dermatan sulfate
Synonyms
1. ChnB
2. chonB
3. chondroitinase B activity
4. dermatan sulfate lyase activity
References
1. EC 4.2.2.19
2. MetaCyc 4.2.2.19-RXN
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// tissue/ enzyme/ localization link to BRENDA
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