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Gene ontology
Version 2014-12-22
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Details for methionine adenosyltransferase activity
2.5.1.6
Gene ontology ID
GO:0004478
Definition
Catalysis of the reaction: ATP + L-methionine + H2O = phosphate + diphosphate + S-adenosyl-L-methionine
Synonyms
1. adenosylmethionine synthetase activity
2. AdoMet synthetase activity
3. ATP-methionine adenosyltransferase activity
4. ATP:L-methionine S-adenosyltransferase activity
5. methionine S-adenosyltransferase activity
6. methionine-activating enzyme
7. S-adenosyl-L-methionine synthetase activity
8. S-adenosylmethionine synthase activity
9. S-adenosylmethionine synthetase activity
References
1. EC 2.5.1.6
2. MetaCyc S-ADENMETSYN-RXN
3. Reactome: R-HSA-174391 "MAT1A multimers transfer Ado from ATP to L-Met"
4. Reactome: R-HSA-5603087 "Defective MAT1A does not transfer Ado from ATP to L-Met"
5. Reactome: R-HSA-5603114 "MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met"
6. RHEA: 21080
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