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BRENDA support

Ontology explorer

Gene ontology
Version 2014-12-22
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Details for sterol regulatory element binding protein cleavage
Gene ontology ID
GO:0035103
Definition
The proteolytic release of a transcriptionally active sterol regulatory element binding protein (SREBP) from intracellular membranes, freeing it to move to the nucleus to upregulate transcription of target genes, in response to altered levels of one or more lipids
Synonyms
1. SREBP cleavage
2. sterol depletion response, SREBP cleavage
3. sterol regulatory element binding protein cleavage involved in ER-nuclear sterol response pathway
References
1. GOC: bf
2. GOC: vw
3. PMID 12923525
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// at least 1 tissue/ enzyme/ localization link in this branch
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