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Ontology explorer

Gene ontology
Version 2014-12-22
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5 different search results found


Details for maintenance of blood-brain barrier
Gene ontology ID
GO:0035633
Definition
Maintaining the structure and function of the blood-brain barrier, thus ensuring specific regulated transport of substances (e.g. macromolecules, small molecules, ions) into the brain, and out of the brain into the blood circulation
Comment
Homeostasis and maintenance processes are regulatory processes, therefore, regulation child terms, such as: regulation of maintenance of blood-brain barrier, should not exist for these terms. \nInstead, for capturing regulation at the blood-brain barrier, consider using the part_of child term: regulation of blood-brain barrier permeability.
Synonyms
1. maintenance of BBB
2. maintenance of blood/brain barrier
References
1. GOC: aruk
2. GOC: bc
3. GOC: bf
4. GOC: sl
5. PMID 20080302
6. PMID 30280653
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
biological_process is a
biological regulation is a
negative regulation of natural killer cell differentiation is a
regulation of biological quality is a
homeostatic process is a
anatomical structure homeostasis is a
tissue homeostasis is a
maintenance of blood-brain barrier is a
ubiquitin recycling is a
synchronous neurotransmitter secretion is a
L-glutamate import across plasma membrane is a
sinoatrial valve morphogenesis is a
female gonad development is a
endocardium development part of
blastocyst hatching part of
blood vessel development is a
artery development is a
response to gibberellin is a
response to bismuth is a
response to peptide is a
peg and socket contact is a
inner dense plaque of desmosome part of
extrinsic component of external side of cell outer membrane part of
Hrd1p ubiquitin ligase ERAD-L complex is a
oligosaccharyltransferase II complex is a
Tree view
Gene ontology
biological_process is a
behavior is a
biological adhesion is a
biological phase is a
biological regulation is a
negative regulation of phosphatidylcholine metabolic process is a
regulation of biological process is a
negative regulation of natural killer cell differentiation involved in immune response is a
regulation of biological quality is a
homeostatic process is a
anatomical structure homeostasis is a
germ-line stem-cell niche homeostasis is a
muscle cell cellular homeostasis is a
neuron cellular homeostasis is a
telomere maintenance is a
tissue homeostasis is a
amnioserosa maintenance is a
bone resorption is a
cartilage homeostasis is a
chemical homeostasis within a tissue is a
compartment boundary maintenance is a
epithelial structure maintenance is a
homeostasis of number of cells within a tissue is a
maintenance of blood-brain barrier is a
maintenance of lens transparency is a
retina homeostasis is a
B cell homeostatic proliferation part of
cellular homeostasis is a
cell volume homeostasis is a
cellular water homeostasis is a
negative regulation of cell volume is a
positive regulation of cell volume is a
cellular chemical homeostasis is a
intracellular accumulation of glycerol is a
ubiquitin recycling is a
free ubiquitin chain depolymerization part of
free ubiquitin chain polymerization part of
chemical homeostasis is a
homeostasis of number of cells is a
multicellular organismal homeostasis is a
regulation of liquid surface tension is a
maintenance of location is a
modulation of age-related behavioral decline is a
regulation of anatomical structure size is a
regulation of appetite is a
regulation of blood pressure is a
regulation of body fluid levels is a
regulation of brood size is a
regulation of buoyancy is a
regulation of circulating fibrinogen levels is a
regulation of DNA stability is a
regulation of hormone levels is a
regulation of membrane lipid distribution is a
regulation of membrane permeability is a
negative regulation of membrane permeability is a
positive regulation of membrane permeability is a
positive regulation of lysosomal membrane permeability is a
positive regulation of mitochondrial membrane permeability is a
regulation of lysosomal membrane permeability is a
regulation of mitochondrial membrane permeability is a
regulation of membrane potential is a
regulation of neurotransmitter levels is a
glutamate reuptake is a
regulation of nucleosome density is a
regulation of postsynaptic membrane neurotransmitter receptor levels is a
regulation of protein complex stability is a
regulation of protein stability is a
regulation of R8 cell spacing in compound eye is a
regulation of synapse structure or activity is a
regulation of translational fidelity is a
regulation of tube architecture, open tracheal system is a
regulation of vascular permeability is a
regulation of molecular function is a
biomineralization is a
carbohydrate utilization is a
carbon utilization is a
cellular process is a
actin filament-based process is a
cell activation is a
cell adhesion molecule production is a
cell aggregation is a
cell communication is a
cell cycle is a
cell death is a
cell division is a
cell growth is a
cell killing is a
cell population proliferation is a
cell recognition is a
cell wall organization or biogenesis is a
cell-cell fusion is a
cellular component organization or biogenesis is a
cellular detoxification is a
cellular developmental process is a
cellular localization is a
cellular metabolic process is a
cellular pigmentation is a
cellular process involved in reproduction in multicellular organism is a
cellular response to stimulus is a
chromosome segregation is a
cytolysis is a
DNA clamp unloading is a
ensheathment of neurons is a
establishment or maintenance of cell polarity is a
establishment or maintenance of cell type involved in phenotypic switching is a
export from cell is a
intercellular transport is a
intermediate filament-based process is a
light absorption is a
localization of cell is a
membrane docking is a
microtubule organizing center localization is a
microtubule-based process is a
movement of cell or subcellular component is a
multi-organism cellular process is a
phenotypic switching is a
plasmid maintenance is a
process utilizing autophagic mechanism is a
protein folding is a
protein unfolding is a
RNA folding is a
signaling receptor ligand precursor processing is a
stomatal movement is a
syncytium formation is a
transmembrane transport is a
(+)-abscisic acid D-glucopyranosyl ester transmembrane transport is a
autoinducer AI-2 transmembrane transport is a
azole transmembrane transport is a
carbohydrate transmembrane transport is a
drug transmembrane transport is a
export across cell outer membrane is a
import across plasma membrane is a
ion transmembrane transport is a
anion transmembrane transport is a
3'-phospho-5'-adenylyl sulfate transmembrane transport is a
5'-adenylyl sulfate transmembrane transport is a
acetyl-CoA transmembrane transport is a
anion transmembrane transporter activity part of
arsenate ion transmembrane transport is a
carboxylic acid transmembrane transport is a
CMP-N-acetylneuraminate transmembrane transport is a
coenzyme A transmembrane transport is a
FAD transmembrane transport is a
glutathione transmembrane transport is a
glycerol-2-phosphate transmembrane transport is a
glycerol-3-phosphate transmembrane transport is a
glycerophosphodiester transmembrane transport is a
inorganic anion transmembrane transport is a
mitochondrial ADP transmembrane transport is a
plasma membrane selenite transport is a
triose phosphate transmembrane transport is a
UDP-galactose transmembrane transport is a
UDP-glucose transmembrane transport is a
UDP-N-acetylgalactosamine transmembrane transport is a
UDP-N-acetylglucosamine transmembrane transport is a
UDP-xylose transmembrane transport is a
cation transmembrane transport is a
establishment or maintenance of transmembrane electrochemical gradient is a
inorganic ion transmembrane transport is a
ion transmembrane transporter activity part of
mobile ion carrier activity part of
mitochondrial transmembrane transport is a
nucleoside transmembrane transport is a
nucleotide transmembrane transport is a
nucleotide-sugar transmembrane transport is a
oligopeptide transmembrane transport is a
organic acid transmembrane transport is a
organomercurial transport is a
phytochelatin transmembrane transport is a
polyamine transmembrane transport is a
protein transmembrane transport is a
purine-containing compound transmembrane transport is a
pyrimidine-containing compound transmembrane transport is a
sterol transmembrane transport is a
transmembrane transporter activity part of
urea transmembrane transport is a
vacuolar transmembrane transport is a
vitamin transmembrane transport is a
transposition is a
vacuolar transport is a
vesicle-mediated transport is a
detoxification is a
developmental process is a
luteinization part of
luteolysis part of
ovarian follicle development part of
ovulation from ovarian follicle part of
endocardial endothelium development part of
artery development is a
aorta development is a
venous blood vessel development is a
growth is a
immune system process is a
interspecies interaction between organisms is a
intraspecies interaction between organisms is a
localization is a
locomotion is a
metabolic process is a
multi-organism process is a
multicellular organismal process is a
pigmentation is a
reproduction is a
response to stimulus is a
detection of stimulus is a
response to abiotic stimulus is a
response to activity is a
response to biotic stimulus is a
response to chemical is a
chemotropism part of
response to acid chemical is a
response to antibiotic is a
response to 4'-epidoxorubicin is a
response to 5-fluoro-2'-deoxyuridine is a
response to actinomycin D is a
response to antimycin A is a
response to bacteriocin is a
response to bleomycin is a
response to brefeldin A is a
response to chloramphenicol is a
response to chloroquine is a
response to cordycepin is a
response to curcumin is a
response to cyclosporin A is a
response to cytarabine is a
response to diosgenin is a
response to doxorubicin is a
response to erythromycin is a
response to ethanol is a
response to farnesol is a
response to formaldehyde is a
response to forskolin is a
response to fungicide is a
response to gemcitabine is a
response to hydrogen peroxide is a
response to micafungin is a
response to miconazole is a
response to papulacandin B is a
response to puromycin is a
response to quercetin is a
response to rapamycin is a
response to reverse transcriptase inhibitor is a
response to sodium arsenite is a
response to tert-butyl hydroperoxide is a
response to tetracycline is a
response to trichodermin is a
response to trichostatin A is a
response to tunicamycin is a
response to antimetabolite is a
response to aromatase inhibitor is a
response to arsenic-containing substance is a
response to asparaginase is a
response to boron-containing substance is a
response to drug is a
response to food is a
response to inorganic substance is a
response to irinotecan is a
response to nitrogen compound is a
response to amyloid-beta is a
response to glutathione is a
response to peptide hormone is a
response to nutrient is a
response to odorant is a
response to organic substance is a
response to oxygen-containing compound is a
response to salt is a
response to TNF agonist is a
response to topoisomerase inhibitor is a
response to toxic substance is a
response to transition metal nanoparticle is a
response to xenobiotic stimulus is a
response to endogenous stimulus is a
response to estrogen is a
response to external stimulus is a
response to inactivity is a
response to redox state is a
response to stress is a
rhythmic process is a
signaling is a
cellular_component is a
cell is a
cellular anatomical entity is a
A band is a727 BRENDA localization in branch, click for list of all
acroblast is a
acrosomal matrix is a724 BRENDA localization in branch, click for list of all
actin body is a
actin cap is a723 BRENDA localization in branch, click for list of all
actin filament branch point is a
actin filament bundle is a
actin fusion focus is a
actin wave is a
actomyosin is a717 BRENDA localization in branch, click for list of all
actomyosin contractile ring, distal actin filament layer is a
actomyosin contractile ring, intermediate layer is a
actomyosin contractile ring, proximal layer is a
alae of collagen and cuticulin-based cuticle extracellular matrix is a
annular furrow extracellular matrix is a
annuli extracellular matrix is a
apical complex is a716 BRENDA localization in branch, click for list of all
apical cytoplasm is a
apical lamina of hyaline layer is a
apical part of cell is a711 BRENDA localization in branch, click for list of all
ascus epiplasm is a
assemblon is a
axon collateral is a709 BRENDA localization in branch, click for list of all
axon hillock is a708 BRENDA localization in branch, click for list of all
axon initial segment is a707 BRENDA localization in branch, click for list of all
axonemal basal plate is a
axonemal central apparatus is a
axonemal outer doublet is a702 BRENDA localization in branch, click for list of all
axoneme is a701 BRENDA localization in branch, click for list of all
bacterial biofilm matrix surface is a
bacterial-type flagellum basal body is a
bacterial-type flagellum filament is a
bacterial-type flagellum hook is a
bacterial-type flagellum hook-filament junction is a
basal labyrinth is a
basal layer of collagen and cuticulin-based cuticle extracellular matrix is a
basal part of cell is a
basolateral cytoplasm is a
bilobe structure is a
blood microparticle is a
Casparian strip is a
cell body is a696 BRENDA localization in branch, click for list of all
cell division site is a693 BRENDA localization in branch, click for list of all
cell junction is a688 BRENDA localization in branch, click for list of all
cell leading edge is a
cell periphery is a651 BRENDA localization in branch, click for list of all
cell cortex part of38 BRENDA localization in branch, click for list of all
external encapsulating structure part of25 BRENDA localization in branch, click for list of all
plasma membrane part of611 BRENDA localization in branch, click for list of all
cell envelope 133 BRENDA localization in branch, click for list of all
cell trailing edge membrane part of
cellular bud membrane part of
cornified envelope is a132 BRENDA localization in branch, click for list of all
cytoplasmic side of plasma membrane part of
cytoproct part of
cytostome part of
endomembrane system 130 BRENDA localization in branch, click for list of all
clathrin-coated pit part of
endoplasmic reticulum part of64 BRENDA localization in branch, click for list of all
endosome part of50 BRENDA localization in branch, click for list of all
Golgi apparatus part of39 BRENDA localization in branch, click for list of all
nuclear envelope part of30 BRENDA localization in branch, click for list of all
nuclear outer membrane-endoplasmic reticulum membrane network part of
omegasome part of21 BRENDA localization in branch, click for list of all
retromer complex part of
secretory granule part of20 BRENDA localization in branch, click for list of all
spitzenkorper part of
transport vesicle part of64 BRENDA localization in branch, click for list of all
external side of plasma membrane part of
extrinsic component of plasma membrane part of
growth cone membrane part of
immunological synapse part of62 BRENDA localization in branch, click for list of all
intrinsic component of plasma membrane part of
lateral plasma membrane part of53 BRENDA localization in branch, click for list of all
mesosome part of52 BRENDA localization in branch, click for list of all
orthogonal array part of51 BRENDA localization in branch, click for list of all
phagocytic cup part of50 BRENDA localization in branch, click for list of all
plasma membrane protein complex part of49 BRENDA localization in branch, click for list of all
plasma membrane region part of
plasma membrane respirasome part of
plasma membrane-derived thylakoid lumen part of
porosome part of3 BRENDA localization in branch, click for list of all
sarcolemma is a2 BRENDA localization in branch, click for list of all
sperm plasma membrane is a
tetraspanin-enriched microdomain part of
unencapsulated part of cell
cell plate is a476 BRENDA localization in branch, click for list of all
cell pole is a475 BRENDA localization in branch, click for list of all
cell projection is a
cell septum is a468 BRENDA localization in branch, click for list of all
cell surface is a467 BRENDA localization in branch, click for list of all
cell tip is a
cell trailing edge is a
cellular bud is a
central element is a465 BRENDA localization in branch, click for list of all
central plaque of spindle pole body is a
centriolar satellite is a
centrosomal corona is a
chiasma is a464 BRENDA localization in branch, click for list of all
chromatin is a463 BRENDA localization in branch, click for list of all
chromosomal region is a446 BRENDA localization in branch, click for list of all
cnida is a
compact myelin is a440 BRENDA localization in branch, click for list of all
concave side of sperm head is a
cone matrix sheath is a
contractile ring is a439 BRENDA localization in branch, click for list of all
cortical layer of collagen and cuticulin-based cuticle extracellular matrix is a
costamere is a
cytoophidium is a438 BRENDA localization in branch, click for list of all
cytoplasm is a437 BRENDA localization in branch, click for list of all
deep fiber is a
dense fibrillar component is a250 BRENDA localization in branch, click for list of all
dense nuclear body is a
dinoflagellate antapex is a
dinoflagellate apex is a
dinoflagellate epicone is a
dinoflagellate hypocone is a
DNA replication termination region is a
eisosome is a249 BRENDA localization in branch, click for list of all
endonuclear canal is a248 BRENDA localization in branch, click for list of all
endospore core is a
ensheathing process is a
envelope is a247 BRENDA localization in branch, click for list of all
epicuticle of collagen and cuticulin-based cuticle extracellular matrix is a
extracellular matrix is a246 BRENDA localization in branch, click for list of all
extracellular region is a230 BRENDA localization in branch, click for list of all
extrachromosomal circular DNA is a212 BRENDA localization in branch, click for list of all
extrachromosomal DNA is a211 BRENDA localization in branch, click for list of all
extrinsic component of membrane is a
fibrillar center is a
Flemming body is a
gas vesicle shell is a
germ tube is a209 BRENDA localization in branch, click for list of all
granular component is a208 BRENDA localization in branch, click for list of all
half bridge of spindle pole body is a
host cellular component is a
incipient cellular bud site is a
inclusion body is a193 BRENDA localization in branch, click for list of all
inner membrane pellicle complex is a
inner plaque of spindle pole body is a
intermediate layer of spindle pole body is a
intracellular immature spore is a
intrinsic component of membrane is a
investment cone is a
lateral element is a
lateral loop is a
lateral part of cell is a
leaflet of membrane bilayer is a
manchette is a183 BRENDA localization in branch, click for list of all
median body is a
membrane is a182 BRENDA localization in branch, click for list of all
membrane-enclosed lumen is a
metaphase plate is a119 BRENDA localization in branch, click for list of all
microtubule bundle is a
microtubule end is a118 BRENDA localization in branch, click for list of all
microtubule organizing center is a116 BRENDA localization in branch, click for list of all
midbody is a107 BRENDA localization in branch, click for list of all
myelin sheath is a106 BRENDA localization in branch, click for list of all
neck portion of tanycyte is a
nucleoid is a105 BRENDA localization in branch, click for list of all
nucleus lagging edge is a
nucleus leading edge is a
oral apparatus is a103 BRENDA localization in branch, click for list of all
organelle is a102 BRENDA localization in branch, click for list of all
pellicle is a10 BRENDA localization in branch, click for list of all
periplasmic space is a9 BRENDA localization in branch, click for list of all
photoreceptor inner segment is a8 BRENDA localization in branch, click for list of all
polar tube is a7 BRENDA localization in branch, click for list of all
site of polarized growth is a6 BRENDA localization in branch, click for list of all
somatodendritic compartment is a
sperm head is a5 BRENDA localization in branch, click for list of all
sperm head-tail coupling apparatus is a
sporoplasm is a
subapical part of cell is a
supramolecular complex is a4 BRENDA localization in branch, click for list of all
symplast is a3 BRENDA localization in branch, click for list of all
tail portion of tanycyte is a
thylakoid is a2 BRENDA localization in branch, click for list of all
Yb body is a
intracellular is a81 BRENDA localization in branch, click for list of all
other organism part is a
protein-containing complex is a55 BRENDA localization in branch, click for list of all
virion is a9 BRENDA localization in branch, click for list of all
molecular_function is a