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BRENDA support

Ontology explorer

Gene ontology
Version 2014-12-22
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7 different search results found


Details for sphingomyelin phosphodiesterase activity
3.1.4.12
Gene ontology ID
GO:0004767
Definition
Catalysis of the reaction: H(2)O + sphingomyelin = ceramide + choline phosphate + H(+)
Synonyms
1. sphingomyelin cholinephosphohydrolase activity
2. sphingomyelinase activity
References
1. EC 3.1.4.12
2. RHEA: 19253
3. KEGG REACTION: R02541
4. MetaCyc SPHINGOMYELIN-PHOSPHODIESTERASE-RXN
5. Reactome: R-HSA-1605797 "Sphingomyelin phosphodiesterase (SMPD1) hydrolyses sphingomyelin to ceramide (lysosome)"
6. Reactome: R-HSA-1606273 "Sphingomyelin phosphodiesterase 2 and 3 (SMPD2 and 3) hydrolyse sphingomyelin to ceramide (plasma membrane)"
7. Reactome: R-HSA-1606288 "Sphingomyelin phosphodiesterase 4 (SMPD4) hydrolyses sphingomyelin to ceramide (ER membrane)"
8. Reactome: R-HSA-1640164 "Ectonucleotide pyrophosphatase/phosphodiesterase 7 (ENPP7) hydrolyses sphingomyelin"
9. Reactome: R-HSA-193706 "Production of ceramide which can activate JNK and other targets"
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
biological_process is a
mediolateral intercalation is a
substrate-independent telencephalic tangential interneuron migration is a
potassium ion uniporter activity is a
sodium-dependent multivitamin transmembrane transporter activity is a
xanthosine:proton symporter activity is a
phosphate:proton symporter activity is a
peg and socket contact is a
inner dense plaque of desmosome part of
extrinsic component of external side of cell outer membrane part of
Hrd1p ubiquitin ligase ERAD-L complex is a
dendritic microtubule part of
telodendria is a
plasma membrane-derived thylakoid lumen part of
leaf papilla is a
stigma papilla is a
trichome papilla is a
host cell cytosol is a
infected host cell surface knob is a
host chromosome is a1 BRENDA localization in branch, click for list of all
host cytoskeleton is a
host intracellular membrane-bounded organelle is a
molecular_function is a
CENP-A containing nucleosome binding is a
nucleosomal histone binding is a
mitochondrial single-subunit type RNA polymerase binding is a
hypocretin receptor binding is a
retinoic acid receptor binding is a
activating MHC class Ib receptor activity is a
catalytic activity is a
tRNA-5-taurinomethyluridine 2-sulfurtransferase is a
hydrolase activity is a
beta-diketone hydrolase activity is a
hydrolase activity, acting on ester bonds is a
lipase activity is a
phospholipase activity is a
sphingomyelin phosphodiesterase activity is a
S-succinylglutathione hydrolase activity is a
chitinase activity is a
endochitinase activity is a
endoglycosylceramidase activity is a
UDP-glucosamine 4-epimerase activity is a
aliphatic aldoxime dehydratase activity is a
adenosylcobinamide-phosphate synthase activity is a
Tree view
Gene ontology
biological_process is a
behavior is a
biological adhesion is a
biological phase is a
biological regulation is a
biomineralization is a
carbohydrate utilization is a
carbon utilization is a
cellular process is a
actin filament-based process is a
cell activation is a
cell adhesion molecule production is a
cell aggregation is a
cell communication is a
cell cycle is a
cell death is a
cell division is a
cell growth is a
cell killing is a
cell population proliferation is a
cell recognition is a
cell wall organization or biogenesis is a
cell-cell fusion is a
cellular component organization or biogenesis is a
cellular detoxification is a
cellular developmental process is a
cellular localization is a
cellular metabolic process is a
bioluminescence is a
cellular alcohol metabolic process is a
cellular aldehyde metabolic process is a
cellular alkane metabolic process is a
cellular alkene metabolic process is a
cellular alkyne metabolic process is a
cellular aromatic compound metabolic process is a
cellular biosynthetic process is a
antibiotic biosynthetic process is a
cellular carbohydrate biosynthetic process is a
cellular macromolecule biosynthetic process is a
cellular nitrogen compound biosynthetic process is a
alkaloid biosynthetic process is a
amide biosynthetic process is a
allantoin biosynthetic process is a
ansamycin biosynthetic process is a
asparagine biosynthetic process is a
biotin biosynthetic process is a
cellular lactam biosynthetic process is a
ceramide biosynthetic process is a
dethiobiotin biosynthetic process is a
fatty acid primary amide biosynthetic process is a
formamide biosynthetic process is a
ochratoxin A biosynthetic process is a
pantothenate biosynthetic process is a
peptide biosynthetic process is a
antimicrobial peptide biosynthetic process is a
bradykinin biosynthetic process is a
carnosine biosynthetic process is a
depsipeptide biosynthetic process is a
gramicidin S biosynthetic process is a
leukotriene D4 biosynthetic process is a
nonribosomal peptide biosynthetic process is a
phytochelatin biosynthetic process is a
pseurotin A biosynthetic process is a
pyrrolysine biosynthetic process is a
spermidine hydroxycinnamate conjugate biosynthetic process is a
sphingomyelin biosynthetic process is a
tensidol A biosynthetic process is a
tensidol B biosynthetic process is a
urea cycle is a
ureide biosynthetic process is a
amine biosynthetic process is a
amino-acid betaine biosynthetic process is a
carbamoyl phosphate biosynthetic process is a
cyanate biosynthetic process is a
cyanide biosynthetic process is a
dipyrrin biosynthetic process is a
flavin-containing compound biosynthetic process is a
nitrile biosynthetic process is a
phytosphingosine biosynthetic process is a
pyridine-containing compound biosynthetic process is a
pyrimidine-containing compound biosynthetic process is a
pyrroloquinoline quinone biosynthetic process is a
sphinganine biosynthetic process is a
sphingosine biosynthetic process is a
cofactor biosynthetic process is a
glycerol ether biosynthetic process is a
glycerolipid biosynthetic process is a
heterocycle biosynthetic process is a
isoprenoid biosynthetic process is a
ketone biosynthetic process is a
ketone body biosynthetic process is a
membrane lipid biosynthetic process is a
mucilage biosynthetic process is a
neutral lipid biosynthetic process is a
organic acid biosynthetic process is a
organic phosphonate biosynthetic process is a
organomercury biosynthetic process is a
peptidyl-dehydroalanine biosynthetic process from peptidyl-tyrosine or peptidyl-serine is a
peptidyl-diphthine biosynthetic process from peptidyl-histidine is a
peptidyl-thyronine biosynthetic process from peptidyl-tyrosine is a
phospholipid biosynthetic process is a
polyphosphate biosynthetic process is a
rhodopsin biosynthetic process is a
sulfur compound biosynthetic process is a
toxin biosynthetic process is a
vitamin biosynthetic process is a
cellular carbohydrate metabolic process is a
cellular catabolic process is a
cellular ketone body metabolic process is a
cellular ketone metabolic process is a
cellular lipid metabolic process is a
cellular macromolecule metabolic process is a
cellular metabolic compound salvage is a
cellular modified amino acid metabolic process is a
cellular nitrogen compound metabolic process is a
cellular organohalogen metabolic process is a
chemosynthesis is a
cofactor metabolic process is a
drug metabolic process is a
generation of precursor metabolites and energy is a
heterocycle metabolic process is a
hydroperoxide metabolic process is a
metabolite repair is a
mucilage metabolic process is a
one-carbon metabolic process is a
organic acid metabolic process is a
organometal metabolic process is a
phosphorus metabolic process is a
photosynthesis is a
prenylation is a
reactive oxygen species metabolic process is a
selenium compound metabolic process is a
sulfur compound metabolic process is a
toxin metabolic process is a
xenobiotic metabolic process is a
cellular pigmentation is a
cellular process involved in reproduction in multicellular organism is a
cellular response to stimulus is a
chromosome segregation is a
cytolysis is a
DNA clamp unloading is a
ensheathment of neurons is a
establishment or maintenance of cell polarity is a
establishment or maintenance of cell type involved in phenotypic switching is a
export from cell is a
intercellular transport is a
intermediate filament-based process is a
light absorption is a
localization of cell is a
interneuron migration from the subpallium to the cortex is a
interneuron sorting involved in substrate-independent cerebral cortex tangential migration part of
membrane docking is a
microtubule organizing center localization is a
microtubule-based process is a
movement of cell or subcellular component is a
multi-organism cellular process is a
phenotypic switching is a
plasmid maintenance is a
process utilizing autophagic mechanism is a
protein folding is a
protein unfolding is a
RNA folding is a
signaling receptor ligand precursor processing is a
stomatal movement is a
syncytium formation is a
transmembrane transport is a
transposition is a
vacuolar transport is a
vesicle-mediated transport is a
detoxification is a
developmental process is a
abscission is a
acquisition of mycelium reproductive competence is a
age-dependent general metabolic decline is a
age-related resistance is a
aging is a
anatomical structure arrangement is a
anatomical structure development is a
adenohypophysis development is a
adrenal cortex development is a
aerial mycelium formation is a
ammon gyrus development is a
amygdala development is a
analia development is a
anatomical structure maturation part of
anatomical structure morphogenesis part of
animal organ development is a
adipose tissue development part of
animal organ regeneration is a
bone development is a
brain development is a
brain segmentation part of
central complex development part of
forebrain development part of
hindbrain development part of
fourth ventricle development part of
medulla oblongata development part of
dorsal motor nucleus of vagus nerve development part of
hypoglossal nucleus development part of
inferior olivary nucleus development part of
medullary reticular formation development part of
nucleus ambiguus development part of
retrotrapezoid nucleus development part of
solitary nucleus development part of
vestibular nucleus development part of
metencephalon development part of
rhombomere development part of
midbrain development part of
midbrain-hindbrain boundary development part of
mushroom body development part of
subarachnoid space development part of
trigeminal sensory nucleus development part of
ventricular system development part of
cartilage development is a
embryonic organ development is a
esophagus development is a
fat body development is a
gall bladder development is a
ganglion development is a
genitalia development is a
gland development is a
gonad development is a
heart development is a
hematopoietic or lymphoid organ development is a
imaginal disc development is a
kidney development is a
larynx development is a
lung development is a
Malpighian tubule development is a
mesenchyme development part of
muscle organ development is a
pancreas development is a
placenta development is a
post-embryonic animal organ development is a
respiratory tube development is a
sensory organ development is a
skin development is a
spinal cord development is a
stomach development is a
swim bladder development is a
trachea development is a
ureter development is a
urethra development is a
urinary bladder development is a
uterus development is a
ventral cord development is a
anterior midgut development is a
anther development is a
appendage development is a
ascending aorta development is a
atrial cardiac muscle tissue development is a
beak development is a
blastocyst development is a
blood vessel development is a
brainstem development is a
caecum development is a
conidiophore stalk development is a
cortical collecting duct development is a
cranial skeletal system development is a
cuticle development is a
dermatome development is a
ectodermal placode development is a
extraembryonic membrane development is a
face development is a
floor plate development is a
floral whorl development is a
fruit replum development is a
fruit valve development is a
hard palate development is a
head development is a
Kupffer's vesicle development is a
lymph vessel development is a
mesendoderm development is a
multicellular organism development is a
muscle structure development is a
neural nucleus development is a
optic lobe placode development is a
palisade mesophyll development is a
parietal peritoneum development is a
plant septum development is a
pollen tube development is a
regeneration is a
roof of mouth development is a
sclerotium development is a
serous membrane development is a
socially cooperative development is a
substantia propria of cornea development is a
substrate mycelium formation is a
suspensor development is a
tissue development is a
umbilical cord development is a
dedifferentiation is a
development involved in symbiotic interaction is a
developmental growth is a
developmental maturation is a
developmental process involved in reproduction is a
dormancy process is a
maintenance of cell number is a
spore germination is a
sporulation is a
growth is a
immune system process is a
interspecies interaction between organisms is a
intraspecies interaction between organisms is a
localization is a
locomotion is a
metabolic process is a
multi-organism process is a
multicellular organismal process is a
pigmentation is a
reproduction is a
response to stimulus is a
rhythmic process is a
signaling is a
cellular_component is a
cell is a
cellular anatomical entity is a
A band is a727 BRENDA localization in branch, click for list of all
acroblast is a
acrosomal matrix is a724 BRENDA localization in branch, click for list of all
actin body is a
actin cap is a723 BRENDA localization in branch, click for list of all
actin filament branch point is a
actin filament bundle is a
actin fusion focus is a
actin wave is a
actomyosin is a717 BRENDA localization in branch, click for list of all
actomyosin contractile ring, distal actin filament layer is a
actomyosin contractile ring, intermediate layer is a
actomyosin contractile ring, proximal layer is a
alae of collagen and cuticulin-based cuticle extracellular matrix is a
annular furrow extracellular matrix is a
annuli extracellular matrix is a
apical complex is a716 BRENDA localization in branch, click for list of all
apical cytoplasm is a
apical lamina of hyaline layer is a
apical part of cell is a711 BRENDA localization in branch, click for list of all
ascus epiplasm is a
assemblon is a
axon collateral is a709 BRENDA localization in branch, click for list of all
axon hillock is a708 BRENDA localization in branch, click for list of all
axon initial segment is a707 BRENDA localization in branch, click for list of all
axonemal basal plate is a
axonemal central apparatus is a
axonemal outer doublet is a702 BRENDA localization in branch, click for list of all
axoneme is a701 BRENDA localization in branch, click for list of all
bacterial biofilm matrix surface is a
bacterial-type flagellum basal body is a
bacterial-type flagellum filament is a
bacterial-type flagellum hook is a
bacterial-type flagellum hook-filament junction is a
basal labyrinth is a
basal layer of collagen and cuticulin-based cuticle extracellular matrix is a
basal part of cell is a
basolateral cytoplasm is a
bilobe structure is a
blood microparticle is a
Casparian strip is a
cell body is a696 BRENDA localization in branch, click for list of all
cell division site is a693 BRENDA localization in branch, click for list of all
cell junction is a688 BRENDA localization in branch, click for list of all
cell leading edge is a
cell periphery is a651 BRENDA localization in branch, click for list of all
cell cortex part of38 BRENDA localization in branch, click for list of all
external encapsulating structure part of25 BRENDA localization in branch, click for list of all
plasma membrane part of611 BRENDA localization in branch, click for list of all
cell envelope 133 BRENDA localization in branch, click for list of all
cell trailing edge membrane part of
cellular bud membrane part of
cornified envelope is a132 BRENDA localization in branch, click for list of all
cytoplasmic side of plasma membrane part of
cytoproct part of
cytostome part of
endomembrane system 130 BRENDA localization in branch, click for list of all
external side of plasma membrane part of
extrinsic component of plasma membrane part of
growth cone membrane part of
immunological synapse part of62 BRENDA localization in branch, click for list of all
intrinsic component of plasma membrane part of
lateral plasma membrane part of53 BRENDA localization in branch, click for list of all
mesosome part of52 BRENDA localization in branch, click for list of all
orthogonal array part of51 BRENDA localization in branch, click for list of all
phagocytic cup part of50 BRENDA localization in branch, click for list of all
plasma membrane protein complex part of49 BRENDA localization in branch, click for list of all
plasma membrane region part of
apicolateral plasma membrane is a
basolateral plasma membrane is a40 BRENDA localization in branch, click for list of all
caveola neck is a
cell projection membrane is a
periciliary membrane compartment is a
photoreceptor inner segment membrane is a
plasma membrane bounded cell projection
actin-based cell projection is a
bleb is a
cell hair is a
cilium is a34 BRENDA localization in branch, click for list of all
BBSome part of5 BRENDA localization in branch, click for list of all
centriolar subdistal appendage part of
ciliary basal body part of4 BRENDA localization in branch, click for list of all
ciliary base part of3 BRENDA localization in branch, click for list of all
ciliary cap part of
ciliary inversin compartment part of
ciliary plasm part of
ciliary pocket part of
ciliary rootlet part of2 BRENDA localization in branch, click for list of all
ciliary tip part of
ciliary transition fiber part of
ciliary transition zone part of
motile cilium is a
non-motile cilium is a
9+0 non-motile cilium is a
photoreceptor cell cilium is a
photoreceptor outer segment part of1 BRENDA localization in branch, click for list of all
ring centriole part of
cytoneme is a
dendritic cell dendrite is a
dinoflagellate peduncle is a
glial cell projection is a
invadopodium is a26 BRENDA localization in branch, click for list of all
macropinocytic cup is a
mating projection is a25 BRENDA localization in branch, click for list of all
microspike is a
muscle cell projection is a
neuron projection is a24 BRENDA localization in branch, click for list of all
cone telodendria is a
rod telodendria is a
plasma membrane bounded cell projection cytoplasm part of
podocyte foot is a5 BRENDA localization in branch, click for list of all
podocyte primary projection is a
pollen tube is a4 BRENDA localization in branch, click for list of all
pseudopodium is a
rhabdomere is a2 BRENDA localization in branch, click for list of all
root hair is a1 BRENDA localization in branch, click for list of all
uropod is a1 BRENDA localization in branch, click for list of all
plasma membrane of cell tip is a
plasma membrane raft is a
plasma membrane-derived thylakoid membrane is a
sperm head plasma membrane is a
plasma membrane respirasome part of
plasma membrane-derived thylakoid lumen part of
porosome part of3 BRENDA localization in branch, click for list of all
sarcolemma is a2 BRENDA localization in branch, click for list of all
sperm plasma membrane is a
tetraspanin-enriched microdomain part of
unencapsulated part of cell
cell plate is a476 BRENDA localization in branch, click for list of all
cell pole is a475 BRENDA localization in branch, click for list of all
cell projection is a
cell septum is a468 BRENDA localization in branch, click for list of all
cell surface is a467 BRENDA localization in branch, click for list of all
cell tip is a
cell trailing edge is a
cellular bud is a
central element is a465 BRENDA localization in branch, click for list of all
central plaque of spindle pole body is a
centriolar satellite is a
centrosomal corona is a
chiasma is a464 BRENDA localization in branch, click for list of all
chromatin is a463 BRENDA localization in branch, click for list of all
chromosomal region is a446 BRENDA localization in branch, click for list of all
cnida is a
compact myelin is a440 BRENDA localization in branch, click for list of all
concave side of sperm head is a
cone matrix sheath is a
contractile ring is a439 BRENDA localization in branch, click for list of all
cortical layer of collagen and cuticulin-based cuticle extracellular matrix is a
costamere is a
cytoophidium is a438 BRENDA localization in branch, click for list of all
cytoplasm is a437 BRENDA localization in branch, click for list of all
deep fiber is a
dense fibrillar component is a250 BRENDA localization in branch, click for list of all
dense nuclear body is a
dinoflagellate antapex is a
dinoflagellate apex is a
dinoflagellate epicone is a
dinoflagellate hypocone is a
DNA replication termination region is a
eisosome is a249 BRENDA localization in branch, click for list of all
endonuclear canal is a248 BRENDA localization in branch, click for list of all
endospore core is a
ensheathing process is a
envelope is a247 BRENDA localization in branch, click for list of all
epicuticle of collagen and cuticulin-based cuticle extracellular matrix is a
extracellular matrix is a246 BRENDA localization in branch, click for list of all
extracellular region is a230 BRENDA localization in branch, click for list of all
angiogenin-PRI complex part of
apoplast is a16 BRENDA localization in branch, click for list of all
extracellular ferritin complex part of
extracellular isoamylase complex part of
extracellular organelle part of
extracellular space part of9 BRENDA localization in branch, click for list of all
activin complex part of
bursicon neuropeptide hormone complex part of
classical-complement-pathway C3/C5 convertase complex part of
CNTFR-CLCF1 complex part of
complement component C1 complex part of
complement component C1q complex part of
CRLF-CLCF1 complex part of
fibrinogen complex part of4 BRENDA localization in branch, click for list of all
immunoglobulin complex, circulating part of
IgA immunoglobulin complex, circulating is a
monomeric IgA immunoglobulin complex is a
polymeric IgA immunoglobulin complex is a
dimeric IgA immunoglobulin complex is a
secretory IgA immunoglobulin complex is a
IgD immunoglobulin complex, circulating is a
IgE immunoglobulin complex, circulating is a
IgG immunoglobulin complex, circulating is a
IgM immunoglobulin complex, circulating is a
inhibin complex part of
insulin-like growth factor binding protein complex part of
interleukin-12 complex part of
interleukin-23 complex part of
interleukin-27 complex part of
interleukin-35 complex part of
larval serum protein complex part of
plasma lipoprotein particle part of
reelin complex part of
extrahaustorial matrix part of
extraorganismal space part of
hyaluranon cable part of
intercellular bridge part of3 BRENDA localization in branch, click for list of all
mucus layer part of2 BRENDA localization in branch, click for list of all
perisynaptic space is a
perivitelline space is a
pituitary gonadotropin complex part of
extrachromosomal circular DNA is a212 BRENDA localization in branch, click for list of all
extrachromosomal DNA is a211 BRENDA localization in branch, click for list of all
extrinsic component of membrane is a
fibrillar center is a
Flemming body is a
gas vesicle shell is a
germ tube is a209 BRENDA localization in branch, click for list of all
granular component is a208 BRENDA localization in branch, click for list of all
half bridge of spindle pole body is a
host cellular component is a
host cell centrosome is a
host cell nucleus is a1 BRENDA localization in branch, click for list of all
incipient cellular bud site is a
inclusion body is a193 BRENDA localization in branch, click for list of all
inner membrane pellicle complex is a
inner plaque of spindle pole body is a
intermediate layer of spindle pole body is a
intracellular immature spore is a
intrinsic component of membrane is a
investment cone is a
lateral element is a
lateral loop is a
lateral part of cell is a
leaflet of membrane bilayer is a
manchette is a183 BRENDA localization in branch, click for list of all
median body is a
membrane is a182 BRENDA localization in branch, click for list of all
membrane-enclosed lumen is a
metaphase plate is a119 BRENDA localization in branch, click for list of all
microtubule bundle is a
microtubule end is a118 BRENDA localization in branch, click for list of all
microtubule organizing center is a116 BRENDA localization in branch, click for list of all
midbody is a107 BRENDA localization in branch, click for list of all
myelin sheath is a106 BRENDA localization in branch, click for list of all
neck portion of tanycyte is a
nucleoid is a105 BRENDA localization in branch, click for list of all
nucleus lagging edge is a
nucleus leading edge is a
oral apparatus is a103 BRENDA localization in branch, click for list of all
organelle is a102 BRENDA localization in branch, click for list of all
pellicle is a10 BRENDA localization in branch, click for list of all
periplasmic space is a9 BRENDA localization in branch, click for list of all
photoreceptor inner segment is a8 BRENDA localization in branch, click for list of all
polar tube is a7 BRENDA localization in branch, click for list of all
site of polarized growth is a6 BRENDA localization in branch, click for list of all
somatodendritic compartment is a
sperm head is a5 BRENDA localization in branch, click for list of all
sperm head-tail coupling apparatus is a
sporoplasm is a
subapical part of cell is a
supramolecular complex is a4 BRENDA localization in branch, click for list of all
symplast is a3 BRENDA localization in branch, click for list of all
tail portion of tanycyte is a
thylakoid is a2 BRENDA localization in branch, click for list of all
Yb body is a
intracellular is a81 BRENDA localization in branch, click for list of all
other organism part is a
protein-containing complex is a55 BRENDA localization in branch, click for list of all
virion is a9 BRENDA localization in branch, click for list of all
molecular_function is a
binding is a
2-aminoethylphosphonate binding is a
acyl binding is a
alkene binding is a
amide binding is a
amine binding is a
antigen binding is a
calcium oxalate binding is a
carbohydrate binding is a
carbohydrate derivative binding is a
cargo receptor ligand activity is a
cellulosome binding is a
chromatin binding is a
cofactor binding is a
dinitrosyl-iron complex binding is a
drug binding is a
exogenous protein binding is a
extracellular matrix binding is a
fatty acid derivative binding is a
flavonoid binding is a
heterocyclic compound binding is a
hormone binding is a
hydroxyapatite binding is a
ice binding is a
ion binding is a
kinetochore binding is a
lipid binding is a
metal cluster binding is a
MgATP(2-) binding is a
microfibril binding is a
modified amino acid binding is a
molecular adaptor activity is a
molecular sequestering activity
neurotransmitter binding is a
nitric oxide binding is a
odorant binding is a
organic cyclic compound binding is a
pigment binding is a
poly(3-hydroxyalkanoate) binding is a
polyamine binding is a
protein binding is a
14-3-3 protein binding is a
alpha-catenin binding is a
angiostatin binding is a
antisigma factor binding is a
apolipoprotein binding is a
arrestin family protein binding is a
ATP-dependent protein binding is a
basal transcription machinery binding is a
beta-2-microglobulin binding is a
beta-catenin binding is a
calmodulin binding is a
cell adhesion molecule binding is a
chaperone binding is a
clathrin binding is a
CNBH domain intrinsic ligand binding is a
co-receptor binding is a
complement binding is a
connexin binding is a
copper-dependent protein binding is a
cullin family protein binding is a
cyclin binding is a
cytokine binding is a
cytoskeletal protein binding is a
delta-catenin binding is a
denatured protein binding is a
dynein heavy chain binding is a
dynein intermediate chain binding is a
dynein light chain binding is a
dynein light intermediate chain binding is a
dystroglycan binding is a
endocytic targeting sequence binding is a
enzyme binding is a
extracellular matrix protein binding is a
farnesylated protein binding is a
FBXO family protein binding is a
fibronectin binding is a
G-protein alpha-subunit binding is a
G-protein beta-subunit binding is a
G-protein gamma-subunit binding is a
gamma-catenin binding is a
GDP-dissociation inhibitor binding is a
growth factor binding is a
GTP-dependent protein binding is a
GTPase activating protein binding is a
haptoglobin binding is a
heat shock protein binding is a
hedgehog family protein binding is a
hemoglobin binding is a
hexon binding is a
histone binding is a
identical protein binding is a
importin-alpha family protein binding is a
inhibin binding is a
insulin receptor substrate binding is a
ion channel binding is a
kininogen binding is a
lamin binding is a
MDM2/MDM4 family protein binding is a
misfolded protein binding is a
modification-dependent protein binding is a
nodal binding is a
opsin binding is a
opsonin binding is a
p53 binding is a
phosphatidylinositol 3-kinase binding is a
phosphoprotein binding is a
phytochrome binding is a
poly-glutamine tract binding is a
preprotein binding is a
profilin binding is a
proline-rich region binding is a
protein C-terminus binding is a
protein dimerization activity is a
protein domain specific binding is a
protein kinase A binding is a
protein N-terminus binding is a
protein self-association is a
RBL family protein binding is a
RHG protein domain binding is a
S100 protein binding is a
scaffold protein binding is a
serpin family protein binding is a
signaling receptor binding is a
acetylcholine receptor binding is a
apolipoprotein receptor binding is a
aryl hydrocarbon receptor binding is a
benzodiazepine receptor binding is a
CD154 receptor binding is a
CD4 receptor binding is a
CD70 receptor binding is a
CD8 receptor binding is a
cytokine receptor binding is a
ephrin receptor binding is a
ErbB-2 class receptor binding is a
ErbB-3 class receptor binding is a
ErbB-4 class receptor binding is a
G protein-coupled receptor binding is a
adenosine receptor binding is a
adrenergic receptor binding is a
adrenomedullin receptor binding is a
alpha-latrotoxin receptor binding is a
angiotensin receptor binding is a
bradykinin receptor binding is a
C5a anaphylatoxin chemotactic receptor binding is a
calcitonin receptor binding is a
cannabinoid receptor binding is a
cysteinyl leukotriene receptor binding is a
dopamine receptor binding is a
D1 dopamine receptor binding is a
D2 dopamine receptor binding is a
D3 dopamine receptor binding is a
D4 dopamine receptor binding is a
D5 dopamine receptor binding is a
endothelial differentiation G protein-coupled receptor binding is a
fMet-Leu-Phe receptor binding is a
follicle-stimulating hormone receptor binding is a
frizzled binding is a
G protein-coupled acetylcholine receptor binding is a
G protein-coupled GABA receptor binding is a
G protein-coupled glutamate receptor binding is a
G protein-coupled histamine receptor binding is a
G protein-coupled nucleotide receptor binding is a
G protein-coupled serotonin receptor binding is a
gastric inhibitory polypeptide receptor binding is a
ghrelin receptor binding is a
glucagon receptor binding is a
leukotriene receptor binding is a
lutropin-choriogonadotropic hormone receptor binding is a
melatonin receptor binding is a
motilin receptor binding is a
neuropeptide receptor binding is a
type 1 hypocretin receptor binding is a
type 2 hypocretin receptor binding is a
olfactory receptor binding is a
opioid receptor binding is a
oxytocin receptor binding is a
parathyroid hormone receptor binding is a
platelet activating factor receptor binding is a
prostanoid receptor binding is a
proteinase activated receptor binding is a
secretin receptor binding is a
smoothened binding is a
taste receptor binding is a
thyrotropin-releasing hormone receptor binding is a
urotensin receptor binding is a
vasopressin receptor binding is a
GABA receptor binding is a
glutamate receptor binding is a
growth factor receptor binding is a
high molecular weight kininogen receptor binding is a
hormone receptor binding is a
immunoglobulin receptor binding is a
insulin receptor binding is a
insulin-like growth factor receptor binding is a
intercellular adhesion molecule-3 receptor binding is a
leptin receptor binding is a
lipoprotein particle receptor binding is a
MDA-5 binding is a
MHC protein binding is a
natural killer cell lectin-like receptor binding is a
neurexin family protein binding is a
neuroligin family protein binding is a
neuropilin binding is a
Notch binding is a
patched binding is a
peroxisome proliferator activated receptor binding is a
pheromone activity is a
RAGE receptor binding is a
receptor serine/threonine kinase binding is a
receptor tyrosine kinase-like orphan receptor binding is a
receptor-receptor interaction is a
RIG-I binding is a
Roundabout binding is a
scavenger receptor binding is a
semaphorin receptor binding is a
sevenless binding is a
sulfonylurea receptor binding is a
T cell receptor binding is a
Toll binding is a
Toll-like receptor binding is a
torso binding is a
transferrin receptor binding is a
wishful thinking binding is a
SMAD binding is a
SMC family protein binding is a
SNARE binding is a
SOCS family protein binding is a
splicing factor binding is a
STAT family protein binding is a
sterol-dependent protein binding is a
TAP binding is a
tapasin binding is a
TIMP family protein binding is a
toxin-antitoxin pair type II binding is a
TRAIL binding is a
transcription factor binding is a
translation elongation factor binding is a
translation initiation factor binding is a
ubiquitin-like protein binding is a
unfolded protein binding is a
very-low-density lipoprotein particle binding is a
Wnt-protein binding is a
X11-like protein binding is a
protein-containing complex binding is a
quaternary ammonium group binding is a
selenium binding is a
small molecule binding is a
sulfur compound binding is a
synthetic cannabinoid binding is a
tetrahydrofolyl-poly(glutamate) polymer binding is a
toxic substance binding is a
virion binding is a
catalytic activity is a
catalytic activity, acting on a protein is a
catalytic activity, acting on DNA is a
catalytic activity, acting on RNA is a
cyclase activity is a
hydrolase activity is a
beta-alanyl-dopamine hydrolase activity is a
beta-alanyl-histamine hydrolase activity is a
coenzyme F390-A hydrolase activity is a
coenzyme F390-G hydrolase activity is a
deacetylase activity is a
deaminase activity is a
hydrolase activity, acting on acid anhydrides is a
hydrolase activity, acting on acid carbon-carbon bonds is a
hydrolase activity, acting on acid carbon-phosphorus bonds is a
hydrolase activity, acting on acid halide bonds is a
hydrolase activity, acting on acid phosphorus-nitrogen bonds is a
hydrolase activity, acting on acid sulfur-nitrogen bonds is a
hydrolase activity, acting on acid sulfur-sulfur bonds is a
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds is a
hydrolase activity, acting on carbon-sulfur bonds is a
hydrolase activity, acting on ester bonds is a
aspartyl esterase activity is a
carboxylic ester hydrolase activity is a
DNA-3'-diphospho-5'-guanosine diphosphatase is a
enterochelin esterase activity is a
indole-3-acetyl-beta-1-D-glucose hydrolase activity is a
indole-3-acetyl-beta-4-D-glucose hydrolase activity is a
lipase activity is a
phospholipase activity is a
cardiolipin hydrolase activity is a
N-acylphosphatidylethanolamine-specific phospholipase D activity is a
phospholipase C activity is a
phospholipase D activity is a
sphingomyelin phosphodiesterase activity is a
acid sphingomyelin phosphodiesterase activity is a
neutral sphingomyelin phosphodiesterase activity is a
sphingomyelin phosphodiesterase D activity is a
phosphoric ester hydrolase activity is a
sulfuric ester hydrolase activity is a
thiolester hydrolase activity is a
versiconal hemiacetal acetate esterase activity is a
hydrolase activity, acting on ether bonds is a
hydrolase activity, acting on glycosyl bonds is a
endochitinase activity is a
exochitinase activity is a
isomerase activity is a
(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity is a
4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity is a
cis-trans isomerase activity is a
dihydroneopterin triphosphate 2'-epimerase activity is a
eoxin A4 synthase activity is a
hepoxilin A3 synthase activity is a
hexulose-6-phosphate isomerase activity is a
intramolecular lyase activity is a
intramolecular oxidoreductase activity is a
2-carboxy-2-hydroxy-8-carboxychromene isomerase activity is a
2-hydroxy-7-hydroxymethylchromene-2-carboxylate isomerase activity is a
2-hydroxy-8-methylchromene-2-carboxylate isomerase activity is a
2-hydroxychromene-2-carboxylate isomerase activity is a
2-hydroxytetrahydrofuran isomerase activity is a
capsanthin synthase activity is a
capsorubin synthase activity is a
intramolecular oxidoreductase activity, interconverting aldoses and ketoses is a
intramolecular oxidoreductase activity, interconverting keto- and enol-groups is a
intramolecular oxidoreductase activity, transposing C=C bonds is a
5-carboxymethyl-2-hydroxymuconate delta-isomerase activity is a
aconitate delta-isomerase activity is a
ascopyrone tautomerase activity is a
C-8 sterol isomerase activity is a
cholestenol delta-isomerase activity is a
delta3,5-delta2,4-dienoyl-CoA isomerase activity is a
dodecenoyl-CoA delta-isomerase activity is a
dopachrome isomerase activity is a
isopentenyl-diphosphate delta-isomerase activity is a
isopiperitenone delta-isomerase activity is a
methylitaconate delta-isomerase activity is a
muconolactone delta-isomerase activity is a
polyenoic fatty acid isomerase activity is a
prostaglandin-A1 delta-isomerase activity is a
steroid delta-isomerase activity is a
trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity is a
trans-2-decenoyl-acyl-carrier-protein isomerase activity is a
vinylacetyl-CoA delta-isomerase activity is a
intramolecular oxidoreductase activity, transposing S-S bonds is a
lachrymatory factor synthase activity is a
neoxanthin synthase activity is a
prostaglandin-D synthase activity is a
prostaglandin-E synthase activity is a
prostaglandin-I synthase activity is a
styrene-oxide isomerase activity is a
thromboxane-A synthase activity is a
intramolecular transferase activity is a
N-acylmannosamine-6-phosphate 2-epimerase activity is a
peroxynitrite isomerase activity is a
racemase and epimerase activity is a
sulfoquinovose isomerase activity is a
thiocyanate isomerase activity is a
ligase activity is a
lyase activity is a
peptidoglycan muralytic activity is a
transferase activity is a
molecular transducer activity is a
nutrient reservoir activity is a
protein tag is a
small molecule sensor activity is a
structural molecule activity is a
transcription regulator activity is a
transporter activity is a