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BRENDA support

Ontology explorer

Gene ontology
Version 2014-12-22
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Details for SOCS family protein binding
Gene ontology ID
GO:0097678
Definition
Interacting selectively and non-covalently with any member of the suppressor of cytokine signaling (SOCS) family of proteins. SOCS represent an important mechanism to extinguish cytokine and growth factor receptor signaling. Individual SOCS proteins are typically induced by specific cytokines and growth factors, thereby generating a negative feedback loop. SOCS proteins have important functions in development and homeostasis, and in disease, particularly tumor suppression and anti-inflammatory functions
Synonyms
1. suppressor of cytokine signaling family protein binding
References
1. GOC: mr
2. InterPro: IPR028413
3. PMID 23885323
4. PMID 24705897
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