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Gene ontology
Version 2014-12-22
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Details for IgM immunoglobulin complex, circulating
Gene ontology ID
GO:0071754
Definition
A polymer of five or six IgM core units each composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds; the individual IgM core units are held together via disulfide bonds with a single J chain polypeptide acting as a bridge between two of the polymeric units. Circulating IgM is present in the extracellular space, in mucosal areas or other tissues, or in the blood or lymph
Comment
Note that an IgM immunoglobulin complex has the function of antigen binding if a suitable antigen is available.
Synonyms
1. IgM antibody
References
1. GOC: add
2. ISBN 0781765196
3. PMID 20176268
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