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BRENDA support

Ontology explorer

Gene ontology
Version 2014-12-22
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Details for insulin receptor substrate binding
Gene ontology ID
GO:0043560
Definition
Interacting selectively and non-covalently with any of the insulin receptor substrate (IRS) proteins, adaptor proteins that bind to the transphosphorylated insulin and insulin-like growth factor receptors, are themselves phosphorylated and in turn recruit SH2 domain-containing signaling molecules to form a productive signaling complex
Synonyms
1. insulin receptor substrate [protein] binding
2. IRS [protein] binding
3. IRS binding
References
1. PMID 12829233
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