Details for negative regulation of signal transduction by receptor internalization
Gene ontology ID
GO:0038011
Definition
Any process in which internalization of a signaling receptor stops, prevents, or reduces the frequency, rate or extent of signal transduction. Receptor internalization can attenuate or reduce the strength of signaling by reducing the concentration of cell surface receptors available to ligands
Synonyms
1. negative regulation of signaling pathway by receptor endocytosis
References
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derives from the parent element
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at least 1 tissue/ enzyme/ localization link in this branch
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tissue/ enzyme/ localization link to BRENDA