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Literature summary extracted from

  • Kish, S.J.; Perry, T.L.; Hansen, S.
    Regional distribution of homocarnosine, homocarnosine-carnosine synthetase and homocarnosinase in human brain (1979), J. Neurochem., 32, 1629-1636.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.3.2.11 dithiothreitol
-
 Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
6.3.2.11 1.8
-
 beta-Ala
-
 Homo sapiens
6.3.2.11 8.8
-
 4-aminobutanoate
-
 Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
6.3.2.11 Co2+ activates Homo sapiens
6.3.2.11 Mn2+ activates Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
6.3.2.11 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.3.2.11 brain frontal and temporal cortex, activity decreases rapidly after brain death Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.2.11 ATP + L-His + 4-aminobutanoate
-
 Homo sapiens AMP + phosphate + homocarnosine
-
 ?
6.3.2.11 ATP + L-His + beta-Ala
-
 Homo sapiens ADP + phosphate + carnosine
-
 ?