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Literature summary extracted from

  • Oppenheim, B.; Patchornik, A.
    Formation of D-alanyl-D-alanine and D-alanine from UDPMurNAc-L-Ala-D-isoGlu-L-Lys-D-Ala-D-Ala by extracts of Staphylococcus aureus and Streptococcus faecalis (1974), FEBS Lett., 48, 172-175.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.3.2.4 ATP + Ala + Ala Staphylococcus aureus the finding that the reactions of EC 6.3.2.4 and EC 6.3.2.10 are reversible may represent a functional regulatory mechanism which determines the level of the lysine-containing UDPMurNAc-pentapeptide depending on the intracellular ATP/ADP ratio ?
-
 ?
6.3.2.4 ATP + Ala + Ala Enterococcus faecalis the finding that the reactions of EC 6.3.2.4 and EC 6.3.2.10 are reversible may represent a functional regulatory mechanism which determines the level of the lysine-containing UDPMurNAc-pentapeptide depending on the intracellular ATP/ADP ratio ?
-
 ?
6.3.2.10 ATP + UDP-N-acetylmuramoyl-L-Ala-D-Glu-L-Lys + D-Ala-D-Ala Staphylococcus aureus
-
 ?
-
 ?
6.3.2.10 ATP + UDP-N-acetylmuramoyl-L-Ala-D-Glu-L-Lys + D-Ala-D-Ala Enterococcus faecalis
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.3.2.4 Enterococcus faecalis
-
-
-
6.3.2.4 Staphylococcus aureus
-
-
-
6.3.2.10 Enterococcus faecalis
-
-
-
6.3.2.10 Staphylococcus aureus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.2.4 ATP + Ala + Ala the finding that the reactions of EC 6.3.2.4 and EC 6.3.2.10 are reversible may represent a functional regulatory mechanism which determines the level of the lysine-containing UDPMurNAc-pentapeptide depending on the intracellular ATP/ADP ratio Staphylococcus aureus ?
-
 ?
6.3.2.4 ATP + Ala + Ala the finding that the reactions of EC 6.3.2.4 and EC 6.3.2.10 are reversible may represent a functional regulatory mechanism which determines the level of the lysine-containing UDPMurNAc-pentapeptide depending on the intracellular ATP/ADP ratio Enterococcus faecalis ?
-
 ?
6.3.2.4 ATP + D-Ala + D-Ala r Staphylococcus aureus ADP + phosphate + D-Ala-D-Ala
-
 ?
6.3.2.4 ATP + D-Ala + D-Ala r Enterococcus faecalis ADP + phosphate + D-Ala-D-Ala
-
 ?
6.3.2.10 ATP + UDP-N-acetylmuramoyl-L-Ala-D-Glu-L-Lys + D-Ala-D-Ala r Staphylococcus aureus ADP + phosphate + UDP-N-acetylmuramoyl-L-Ala-D-Glu-L-Lys-D-Ala-D-Ala
-
 ?
6.3.2.10 ATP + UDP-N-acetylmuramoyl-L-Ala-D-Glu-L-Lys + D-Ala-D-Ala r Enterococcus faecalis ADP + phosphate + UDP-N-acetylmuramoyl-L-Ala-D-Glu-L-Lys-D-Ala-D-Ala
-
 ?
6.3.2.10 ATP + UDP-N-acetylmuramoyl-L-Ala-D-Glu-L-Lys + D-Ala-D-Ala
-
 Staphylococcus aureus ?
-
 ?
6.3.2.10 ATP + UDP-N-acetylmuramoyl-L-Ala-D-Glu-L-Lys + D-Ala-D-Ala
-
 Enterococcus faecalis ?
-
 ?