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Literature summary extracted from
- Partial purification and characterization of dipeptidyl peptidase II (DPP II) from guinea pig testes (1986), Gamete Res., 15, 161-175.
No PubMed abstract available
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.14.2 | Cu2+ | 10 mM CuSO4, 23% inhibition | Cavia porcellus |  |
| 3.4.14.2 | K+ | 50 mM KCl, 42% inhibition | Cavia porcellus | |
| 3.4.14.2 | Na+ | 10 mM NaCl, 38% inhibition | Cavia porcellus | |
| 3.4.14.2 | p-Nitrophenyl-p-guanidinobenzoate | 1 mM, 43% inhibition | Cavia porcellus | |
| 3.4.14.2 | phenylmethylsulfonyl fluoride | 1 mM, 15% inhibition | Cavia porcellus | |
| 3.4.14.2 | Tris | 50 mM, 97% inhibition | Cavia porcellus | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.4.14.2 | 135000 | - |
gel filtration | Cavia porcellus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.14.2 | Cavia porcellus | - |
multiple isoforms | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.4.14.2 | partial, multiple isoforms | Cavia porcellus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.14.2 | testis | - |
Cavia porcellus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.4.14.2 | 27.4 | - |
- |
Cavia porcellus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.14.2 | (Ala)3 + H2O | - |
Cavia porcellus | ? | - |
? | |
| 3.4.14.2 | Lys-Ala-2-(4-methoxy)-naphthylamide Lys-Ala-4-methoxy-2-naphthylamide + H2O | - |
Cavia porcellus | ? | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.4.14.2 | dimer | 2 * 64000-66000, SDS-PAGE | Cavia porcellus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.14.2 | 4.5 | - |
hydrolysis of (Ala)3 | Cavia porcellus |
pH Range
| EC Number | pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.14.2 | 3.7 | 5.8 | pH 3.5: about 85% of maximal activity, pH 5.8: about 45% of maximal activity | Cavia porcellus |
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