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Literature summary extracted from

  • Zammit, V.A.; Beis, A.; Newsholme, E.A.
    The role of 3-oxo acid-CoA transferase in the regulation of ketogenesis in the liver (1979), FEBS Lett., 103, 212-215.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.8.3.5 succinyl-CoA + acetoacetate Gallus gallus liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate ?
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate Mus musculus liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate ?
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate Rattus norvegicus liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate ?
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate Oryctolagus cuniculus liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate ?
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate Oncorhynchus mykiss liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate ?
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate Columba livia liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate ?
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate Scyliorhinus canicula liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate ?
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate Dicentrarchus labrax liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate ?
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate Pleuronectes platessa liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate ?
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate Raja clavata liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate ?
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate Clupea harengus liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate ?
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate Lacerta viridis liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate ?
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate Scomber scombrus liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.8.3.5 Clupea harengus
-
 herring
-
2.8.3.5 Columba livia
-
 domestic pigeon
-
2.8.3.5 Dicentrarchus labrax
-
 bass
-
2.8.3.5 Gallus gallus
-
 domestic fowl
-
2.8.3.5 Lacerta viridis
-
 green lizard
-
2.8.3.5 Mus musculus
-
-
-
2.8.3.5 Oncorhynchus mykiss
-
 rainbow trout
-
2.8.3.5 Oryctolagus cuniculus
-
-
-
2.8.3.5 Pleuronectes platessa
-
 plaice
-
2.8.3.5 Raja clavata
-
 ray
-
2.8.3.5 Rattus norvegicus
-
-
-
2.8.3.5 Scomber scombrus
-
 mackerel
-
2.8.3.5 Scyliorhinus canicula
-
 dogfish
-
3.1.2.11 Columba livia
-
 domestic pigeon
-
3.1.2.11 Gallus gallus
-
 chicken
-
3.1.2.11 Mus musculus
-
-
-
3.1.2.11 Oncorhynchus mykiss
-
 rainbow trout
-
3.1.2.11 Oryctolagus cuniculus
-
-
-
3.1.2.11 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.8.3.5 liver
-
 Gallus gallus
-
2.8.3.5 liver
-
 Mus musculus
-
2.8.3.5 liver
-
 Rattus norvegicus
-
2.8.3.5 liver
-
 Oryctolagus cuniculus
-
2.8.3.5 liver
-
 Oncorhynchus mykiss
-
2.8.3.5 liver
-
 Columba livia
-
2.8.3.5 liver
-
 Scyliorhinus canicula
-
2.8.3.5 liver
-
 Dicentrarchus labrax
-
2.8.3.5 liver
-
 Pleuronectes platessa
-
2.8.3.5 liver
-
 Raja clavata
-
2.8.3.5 liver
-
 Clupea harengus
-
2.8.3.5 liver
-
 Lacerta viridis
-
2.8.3.5 liver
-
 Scomber scombrus
-
3.1.2.11 liver
-
 Gallus gallus
-
3.1.2.11 liver
-
 Mus musculus
-
3.1.2.11 liver
-
 Rattus norvegicus
-
3.1.2.11 liver
-
 Oryctolagus cuniculus
-
3.1.2.11 liver
-
 Oncorhynchus mykiss
-
3.1.2.11 liver
-
 Columba livia
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.3.5 succinyl-CoA + acetoacetate
-
 Gallus gallus succinate + acetoacetyl-CoA
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate
-
 Mus musculus succinate + acetoacetyl-CoA
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate
-
 Rattus norvegicus succinate + acetoacetyl-CoA
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate
-
 Oryctolagus cuniculus succinate + acetoacetyl-CoA
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate
-
 Oncorhynchus mykiss succinate + acetoacetyl-CoA
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate
-
 Columba livia succinate + acetoacetyl-CoA
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate
-
 Scyliorhinus canicula succinate + acetoacetyl-CoA
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate
-
 Dicentrarchus labrax succinate + acetoacetyl-CoA
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate
-
 Pleuronectes platessa succinate + acetoacetyl-CoA
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate
-
 Raja clavata succinate + acetoacetyl-CoA
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate
-
 Clupea harengus succinate + acetoacetyl-CoA
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate
-
 Lacerta viridis succinate + acetoacetyl-CoA
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate
-
 Scomber scombrus succinate + acetoacetyl-CoA
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate Gallus gallus ?
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate Mus musculus ?
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate Rattus norvegicus ?
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate Oryctolagus cuniculus ?
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate Oncorhynchus mykiss ?
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate Columba livia ?
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate Scyliorhinus canicula ?
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate Dicentrarchus labrax ?
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate Pleuronectes platessa ?
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate Raja clavata ?
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate Clupea harengus ?
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate Lacerta viridis ?
-
 ?
2.8.3.5 succinyl-CoA + acetoacetate liver enzyme: produces a substrate circle between acetoacetyl-CoA and acetoacetate Scomber scombrus ?
-
 ?
3.1.2.11 acetoacetyl-CoA + H2O
-
 Gallus gallus acetoacetate + CoA
-
 ?
3.1.2.11 acetoacetyl-CoA + H2O
-
 Mus musculus acetoacetate + CoA
-
 ?
3.1.2.11 acetoacetyl-CoA + H2O
-
 Rattus norvegicus acetoacetate + CoA
-
 ?
3.1.2.11 acetoacetyl-CoA + H2O
-
 Oryctolagus cuniculus acetoacetate + CoA
-
 ?
3.1.2.11 acetoacetyl-CoA + H2O
-
 Oncorhynchus mykiss acetoacetate + CoA
-
 ?
3.1.2.11 acetoacetyl-CoA + H2O
-
 Columba livia acetoacetate + CoA
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.8.3.5 10
-
 assay at, all fish enzymes except Salmo gairdneri Scyliorhinus canicula
2.8.3.5 10
-
 assay at, all fish enzymes except Salmo gairdneri Dicentrarchus labrax
2.8.3.5 10
-
 assay at, all fish enzymes except Salmo gairdneri Pleuronectes platessa
2.8.3.5 10
-
 assay at, all fish enzymes except Salmo gairdneri Raja clavata
2.8.3.5 10
-
 assay at, all fish enzymes except Salmo gairdneri Clupea harengus
2.8.3.5 10
-
 assay at, all fish enzymes except Salmo gairdneri Scomber scombrus
2.8.3.5 25
-
 assay at Gallus gallus
2.8.3.5 25
-
 assay at Mus musculus
2.8.3.5 25
-
 assay at Rattus norvegicus
2.8.3.5 25
-
 assay at Oryctolagus cuniculus
2.8.3.5 25
-
 assay at Oncorhynchus mykiss
2.8.3.5 25
-
 assay at Columba livia
2.8.3.5 25
-
 assay at Lacerta viridis