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Literature summary extracted from

  • Lambert, D.A.; Smith, L.C.; Pownall, H.; Sparrow, J.T.; Nicolas, J.P.; Gotto, A.M.
    Hydrolysis of phospholipids by purified milk lipoprotein lipase. Effect of apoprotein CII, CIII, A and E, and synthetic fragments (2000), Clin. Chim. Acta, 291, 19-33.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.1.34 apolipoprotein C-II cofactor Bos taurus
3.1.1.34 apoprotein CII 100% and 300% of increase in LPL activity for phosphatidyl-choline and triglyceride hydrolysis, respectively Bos taurus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.34 Apo AI 0.001 mM, 25% inhibitiion of 1-myristol-2[9(1-pyrenyl)-nonanoyl]-phosphatidylcholine hydrolysis Bos taurus
3.1.1.34 Apo AII 0.001 mM, 50% inhibitiion of 1-myristol-2[9(1-pyrenyl)-nonanoyl]-phosphatidylcholine hydrolysis Bos taurus
3.1.1.34 Apo CI 0.0005 mM, 72% inhibitiion of 1-myristol-2[9(1-pyrenyl)-nonanoyl]-phosphatidylcholine hydrolysis Bos taurus
3.1.1.34 apolipoprotein A I
-
 Bos taurus
3.1.1.34 apolipoprotein A II
-
 Bos taurus
3.1.1.34 apolipoprotein C I
-
 Bos taurus
3.1.1.34 fragments of apolipoprotein E
-
 Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.34 triacylglycerol + H2O Bos taurus
-
 diacylglycerol + a carboxylate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.34 Bos taurus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.1.34
-
 Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.34 milk
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.34 1,2-ditetradecanoyl-3[9(1-pyrenyl)nonanoyl]glyceride + H2O
-
 Bos taurus ?
-
 ?
3.1.1.34 1,3-dioleoyl-2[4(1-pyrenyl)butanoyl]glycerol + H2O
-
 Bos taurus ?
-
 ?
3.1.1.34 1-lauryl-2[9(1-pyrenyl) nonanoyl]phosphatidylcholine + H2O
-
 Bos taurus ?
-
 ?
3.1.1.34 1-myristol-2[9(1-pyrenyl)-nonanoyl]-phosphatidylcholine + H2O
-
 Bos taurus myristic acid + 2[9(1-pyrenyl)-nonanoyl]-phosphatidylcholine
-
 ?
3.1.1.34 1-myristoyl-2[9(1-pyrenyl)nonanoyl]diglyceride + H2O
-
 Bos taurus ?
-
 ?
3.1.1.34 1-myristoyl-2[9(1-pyrenyl)nonanoyl]phosphatidic acid + H2O
-
 Bos taurus ?
-
 ?
3.1.1.34 1-myristoyl-2[9(1-pyrenyl)nonanoyl]phosphatidylethanolamine + H2O
-
 Bos taurus ?
-
 ?
3.1.1.34 1-myristoyl-2[9(1pyrenyl)nonaoyl]phosphatidylcholine + H2O
-
 Bos taurus ?
-
 ?
3.1.1.34 triacylglycerol + H2O
-
 Bos taurus diacylglycerol + a carboxylate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.1.34 LPL
-
 Bos taurus