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Literature summary extracted from

  • Yang, T.; Li, Y.; Liu, Y.; He, L.; Liu, A.; Wen, J.; Mysore, K.S.; Tadege, M.; Chen, J.
    The 3-ketoacyl-CoA synthase WFL is involved in lateral organ development and cuticular wax synthesis in Medicago truncatula (2021), Plant Mol. Biol., 105, 193-204.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.75 acyl-CoA + a long-chain alcohol Medicago truncatula
-
 CoA + a long-chain ester
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.75 Medicago truncatula
-
 ecotype R108
-
2.3.1.199 Medicago truncatula
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.75 carpel high expression Medicago truncatula
-
2.3.1.75 epidermal cell
-
 Medicago truncatula
-
2.3.1.75 leaf
-
 Medicago truncatula
-
2.3.1.75 petal highest expression Medicago truncatula
-
2.3.1.75 root lowest expression Medicago truncatula
-
2.3.1.75 shoot high expression in vegetative and reproductive shoot Medicago truncatula
-
2.3.1.75 shoot apical meristem
-
 Medicago truncatula
-
2.3.1.75 stamen high expression Medicago truncatula
-
2.3.1.75 stem
-
 Medicago truncatula
-
2.3.1.199 flower
-
 Medicago truncatula
-
2.3.1.199 leaf leaf primordia Medicago truncatula
-
2.3.1.199 additional information broadly expressed in aerial organs Medicago truncatula
-
2.3.1.199 shoot shoot apical meristem Medicago truncatula
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.75 acyl-CoA + a long-chain alcohol
-
 Medicago truncatula CoA + a long-chain ester
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.75 3-ketoacyl-CoA synthase
-
 Medicago truncatula
2.3.1.75 KCS
-
 Medicago truncatula
2.3.1.75 Medtr3g105550
-
 Medicago truncatula
2.3.1.75 WFL
-
 Medicago truncatula
2.3.1.199 Medtr3g105550,
-
 Medicago truncatula

General Information

EC Number General Information Comment Organism
2.3.1.75 malfunction the wfl gene mutants (wrinkled flower and leaf) show sparse epicuticular wax crystals on the leaf surface and increased water permeability in leaves compared to the wild type. The mutation of the enzyme leads to a markedly increased percentage of C20:0, C22:0, and C24:0 fatty acids in leaves, a significantly reduced cuticular wax content, and dramatic changes of wax constituents in leaves Medicago truncatula
2.3.1.75 physiological function the enzyme plays a key role in very long chain fatty acid biosynthesis, cuticular wax formation and in the late stage of leaf and flower development Medicago truncatula
2.3.1.199 physiological function in a Tnt1 insertion line in gene Medtr3g105550, leaves show sparser epicuticular wax crystals on the surface and increased water permeability compared with wild-typeIn mutant leaves, the percentage of C20:0, C22:0, and C24:0 fatty acids is significantly increased, the amount of cuticular wax is markedly reduced, and wax constituents are altered Medicago truncatula