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Literature summary extracted from

  • Kang, S.; Kang, K.; Lee, K.; Back, K.
    Characterization of tryptamine 5-hydroxylase and serotonin synthesis in rice plants (2007), Plant Cell Rep., 26, 2009-2015.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.14.186 5-hydroxy-tryptophan 30% inhibition at 0.5 mM Oryza sativa Japonica Group
1.14.14.186 additional information the enzyme activity remains unaltered by dopamine in vitro Oryza sativa Japonica Group
1.14.14.186 octopamine 35% inhibition at 1 mM Oryza sativa Japonica Group
1.14.14.186 tryptophan 30% inhibition at 0.5 mM Oryza sativa Japonica Group

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.14.14.186 soluble
-
 Oryza sativa Japonica Group
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.14.186 tryptamine + O2 + [reduced NADPH-hemoprotein reductase] Oryza sativa Japonica Group
-
 serotonin + H2O + [oxidized NADPH-hemoprotein reductase]
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.186 Oryza sativa Japonica Group Q2QUC5 cultivar Dongjin
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.14.186 leaf
-
 Oryza sativa Japonica Group
-
1.14.14.186 root highest enzyme activity in roots Oryza sativa Japonica Group
-
1.14.14.186 seed
-
 Oryza sativa Japonica Group
-
1.14.14.186 seed coat lowest enzyme activity in hull Oryza sativa Japonica Group
-
1.14.14.186 seedling
-
 Oryza sativa Japonica Group
-
1.14.14.186 stem
-
 Oryza sativa Japonica Group
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.186 tryptamine + O2 + [reduced NADPH-hemoprotein reductase]
-
 Oryza sativa Japonica Group serotonin + H2O + [oxidized NADPH-hemoprotein reductase]
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.14.186 T5H
-
 Oryza sativa Japonica Group

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.14.186 tetrahydropterine dependent on, the enzyme activity decreases by 70% in the absence of tetrahydropterine Oryza sativa Japonica Group