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Literature summary extracted from

  • Yao, S.; Wei, C.; Lin, H.; Zhang, P.; Liu, Y.; Deng, Y.; Huang, Q.; Xie, B.
    Cystathionine gamma-lyase regulate psilocybin biosynthesis in Gymnopilus dilepis mushroom via amino acid metabolism pathways (2022), J. Fungi (Basel), 8, 870.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.4.1.1 DL-propargylglycine potent inhibitor Gymnopilus dilepis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.4.1.1 L-cystathionine + H2O Gymnopilus dilepis
-
 L-cysteine + 2-oxobutanoate + NH3
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.4.1.1 Gymnopilus dilepis A0A409VQL6
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.4.1.1 L-cystathionine + H2O
-
 Gymnopilus dilepis L-cysteine + 2-oxobutanoate + NH3
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.4.1.1 CTH
-
 Gymnopilus dilepis
4.4.1.1 cth2
-
 Gymnopilus dilepis

General Information

EC Number General Information Comment Organism
4.4.1.1 metabolism the enzyme is closely related to psilocybin synthesis Gymnopilus dilepis