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Literature summary extracted from

  • Fujiwara, T.; Maisonneuve, S.; Isshiki, M.; Mizutani, M.; Chen, L.; Wong, H.L.; Kawasaki, T.; Shimamoto, K.
    Sekiguchi lesion gene encodes a cytochrome P450 monooxygenase that catalyzes conversion of tryptamine to serotonin in rice (2010), J. Biol. Chem., 285, 11308-11313.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.14.186 expressed in Escherichia coli DH10Bac cells and Sf9 insect cells Oryza sativa Japonica Group

Protein Variants

EC Number Protein Variants Comment Organism
1.14.14.186 G455D inactive Oryza sativa Japonica Group

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.14.14.186 endoplasmic reticulum
-
 Oryza sativa Japonica Group 5783
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.14.186 tryptamine + O2 + [reduced NADPH-hemoprotein reductase] Oryza sativa Japonica Group
-
 serotonin + H2O + [oxidized NADPH-hemoprotein reductase]
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.186 Oryza sativa Japonica Group Q2QUC5
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.14.186 leaf
-
 Oryza sativa Japonica Group
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.186 additional information the enzyme does not metabolize tryptophan, indole 3-acetic acid, or tyramine Oryza sativa Japonica Group ?
-
-
1.14.14.186 tryptamine + O2 + [reduced NADPH-hemoprotein reductase]
-
 Oryza sativa Japonica Group serotonin + H2O + [oxidized NADPH-hemoprotein reductase]
-
 ?
1.14.14.186 tryptamine + O2 + [reduced NADPH-P450 reductase]
-
 Oryza sativa Japonica Group serotonin + H2O + [oxidized NADPH-P450 reductase]
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.14.186 CYP71P1
-
 Oryza sativa Japonica Group
1.14.14.186 SL protein
-
 Oryza sativa Japonica Group

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.14.186 cytochrome P450
-
 Oryza sativa Japonica Group
1.14.14.186 heme
-
 Oryza sativa Japonica Group
1.14.14.186 NADPH
-
 Oryza sativa Japonica Group

Expression

EC Number Organism Comment Expression
1.14.14.186 Oryza sativa Japonica Group enzyme expression is induced by the N-acetylchitooligosaccharide (chitin) elicitor and by infection with Magnaporthe grisea up