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Literature summary extracted from

  • Sheppard, D.; Penrod, J.; Bobik, T.; Kofoid, E.; Roth, J.
    Evidence that a B12-adenosyl transferase is encoded within the ethanolamine operon of Salmonella enterica (2004), J. Bacteriol., 186, 7635-7644 .
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.154 Salmonella enterica subsp. enterica serovar Typhimurium Q9ZFV4
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.154 2 ATP + 2 [corrinoid adenosyltransferase]-cob(I)alamin
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 Salmonella enterica subsp. enterica serovar Typhimurium 2 diphosphate + 2 phosphate + 2 adenosylcob(III)alamin + 2 [corrinoid adenosyltransferase]
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 ?

Subunits

EC Number Subunits Comment Organism
2.5.1.154 ? x * 30200, SDS-PAGE, recombinant protein Salmonella enterica subsp. enterica serovar Typhimurium

Synonyms

EC Number Synonyms Comment Organism
2.5.1.154 EutT
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 Salmonella enterica subsp. enterica serovar Typhimurium

Expression

EC Number Organism Comment Expression
2.5.1.154 Salmonella enterica subsp. enterica serovar Typhimurium EutT is encoded within the operon for ethanolamine utilization, Eut additional information

General Information

EC Number General Information Comment Organism
2.5.1.154 physiological function in Salmonlella typhimurium, three types of corrinoid adenosyltransferases have been described. CoBa is a housekeeping enzyme involved in both the de novo biosynthesis and the salvage of adenosylcobalamin. The PduO adenosyl transferase is encoded in an operon (pdu) for cobalamin-dependent propanediol degradation and is induced by propanediol. Transferase EutT is encoded within the operon for ethanolamine utilization (eut). CobA produces sufficient Ado-B12 to initiate eut operon induction and to serve as a cofactor for EA-lyase when B12 levels are high. Once the eut operon is induced, the EutT transferase supplies more Ado-B12 during the period of high demand Salmonella enterica subsp. enterica serovar Typhimurium