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Literature summary extracted from
- Biochemical and expression analyses of the rice cinnamoyl-CoA reductase gene family (2017), Front. Plant Sci., 8, 2099 .
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 1.2.1.44 | isoforms CCR17, CCR19, CCR20, and CCR21 are expressed in Escherichia coli BL21(DE3) cells | Oryza sativa Japonica Group |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.2.1.44 | 0.0027 | - |
feruloyl-CoA | isoform CCR21, at pH 6.3 and 30°C | Oryza sativa Japonica Group |  |
| 1.2.1.44 | 0.0102 | - |
sinapoyl-CoA | isoform CCR21, at pH 6.3 and 30°C | Oryza sativa Japonica Group | |
| 1.2.1.44 | 0.01571 | - |
feruloyl-CoA | isoform CCR20, at pH 6.3 and 30°C | Oryza sativa Japonica Group | |
| 1.2.1.44 | 0.01636 | - |
4-coumaroyl-CoA | isoform CCR21, at pH 6.3 and 30°C | Oryza sativa Japonica Group | |
| 1.2.1.44 | 0.02334 | - |
sinapoyl-CoA | isoform CCR20, at pH 6.3 and 30°C | Oryza sativa Japonica Group | |
| 1.2.1.44 | 0.02408 | - |
4-coumaroyl-CoA | isoform CCR20, at pH 6.3 and 30°C | Oryza sativa Japonica Group | |
| 1.2.1.44 | 0.02685 | - |
feruloyl-CoA | isoform CCR19, at pH 6.3 and 30°C | Oryza sativa Japonica Group | |
| 1.2.1.44 | 0.03666 | - |
4-coumaroyl-CoA | isoform CCR19, at pH 6.3 and 30°C | Oryza sativa Japonica Group | |
| 1.2.1.44 | 0.06254 | - |
sinapoyl-CoA | isoform CCR19, at pH 6.3 and 30°C | Oryza sativa Japonica Group | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.2.1.44 | cinnamoyl-CoA + NADPH + H+ | Oryza sativa Japonica Group | - |
cinnamaldehyde + CoA + NADP+ | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.2.1.44 | Oryza sativa Japonica Group | - |
cultivar Dongjin | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.2.1.44 | Ni-NTA agarose column chromatography | Oryza sativa Japonica Group |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.2.1.44 | leaf | - |
Oryza sativa Japonica Group | - |
| 1.2.1.44 | panicle | highest expression of isoform CCR19 | Oryza sativa Japonica Group | - |
| 1.2.1.44 | root | highest expression of isoform CCR20 and CCR21 | Oryza sativa Japonica Group | - |
| 1.2.1.44 | shoot | highest expression of isoform CCR17 | Oryza sativa Japonica Group | - |
| 1.2.1.44 | stem | - |
Oryza sativa Japonica Group | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.2.1.44 | 4-coumaroyl-CoA + NADPH + H+ | - |
Oryza sativa Japonica Group | 4-coumaraldehyde + CoA + NADP+ | - |
? | |
| 1.2.1.44 | cinnamoyl-CoA + NADPH + H+ | - |
Oryza sativa Japonica Group | cinnamaldehyde + CoA + NADP+ | - |
? | |
| 1.2.1.44 | feruloyl-CoA + NADPH + H+ | - |
Oryza sativa Japonica Group | coniferaldehyde + CoA + NADP+ | - |
? | |
| 1.2.1.44 | sinapoyl-CoA + NADPH + H+ | - |
Oryza sativa Japonica Group | sinapaldehyde + CoA + NADP+ | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 1.2.1.44 | ? | x * 37900, isoform CCR17, calculated from amino acid sequence | Oryza sativa Japonica Group |
| 1.2.1.44 | ? | x * 38600, isoform CCR19, calculated from amino acid sequence | Oryza sativa Japonica Group |
| 1.2.1.44 | ? | x * 38700, isoform CCR20, calculated from amino acid sequence | Oryza sativa Japonica Group |
| 1.2.1.44 | ? | x * 37900, isoform CCR21, calculated from amino acid sequence | Oryza sativa Japonica Group |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.2.1.44 | CCR17 | isoform | Oryza sativa Japonica Group |
| 1.2.1.44 | CCR19 | isoform | Oryza sativa Japonica Group |
| 1.2.1.44 | CCR20 | isoform | Oryza sativa Japonica Group |
| 1.2.1.44 | CCR21 | isoform | Oryza sativa Japonica Group |
Turnover Number [1/s]
| EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.2.1.44 | 0.012 | - |
sinapoyl-CoA | isoform CCR21, at pH 6.3 and 30°C | Oryza sativa Japonica Group | |
| 1.2.1.44 | 0.019 | - |
4-coumaroyl-CoA | isoform CCR21, at pH 6.3 and 30°C | Oryza sativa Japonica Group | |
| 1.2.1.44 | 0.027 | - |
feruloyl-CoA | isoform CCR21, at pH 6.3 and 30°C | Oryza sativa Japonica Group | |
| 1.2.1.44 | 0.094 | - |
sinapoyl-CoA | isoform CCR20, at pH 6.3 and 30°C | Oryza sativa Japonica Group | |
| 1.2.1.44 | 0.129 | - |
4-coumaroyl-CoA | isoform CCR20, at pH 6.3 and 30°C | Oryza sativa Japonica Group | |
| 1.2.1.44 | 0.191 | - |
feruloyl-CoA | isoform CCR19, at pH 6.3 and 30°C | Oryza sativa Japonica Group | |
| 1.2.1.44 | 0.353 | - |
4-coumaroyl-CoA | isoform CCR19, at pH 6.3 and 30°C | Oryza sativa Japonica Group | |
| 1.2.1.44 | 0.377 | - |
feruloyl-CoA | isoform CCR20, at pH 6.3 and 30°C | Oryza sativa Japonica Group | |
| 1.2.1.44 | 0.57 | - |
sinapoyl-CoA | isoform CCR19, at pH 6.3 and 30°C | Oryza sativa Japonica Group | |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.2.1.44 | NADPH | - |
Oryza sativa Japonica Group | |
Expression
| EC Number | Organism | Comment | Expression |
|---|---|---|---|
| 1.2.1.44 | Oryza sativa Japonica Group | the expressions of isoforms CCR17 and 21 are induced in response to biotic and abiotic stresses, such as Magnaporthe grisea and Xanthomonas oryzae pv. oryzae infections, UV-irradiation and high salinity (250 mM NaCl) | up |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 1.2.1.44 | physiological function | isoform CCR20 is primarily involved in developmental deposition of lignins in secondary cell walls | Oryza sativa Japonica Group |
kcat/KM [mM/s]
| EC Number | kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.2.1.44 | 1.17 | - |
sinapoyl-CoA | isoform CCR21, at pH 6.3 and 30°C | Oryza sativa Japonica Group | |
| 1.2.1.44 | 1.33 | - |
4-coumaroyl-CoA | isoform CCR21, at pH 6.3 and 30°C | Oryza sativa Japonica Group | |
| 1.2.1.44 | 4 | - |
sinapoyl-CoA | isoform CCR20, at pH 6.3 and 30°C | Oryza sativa Japonica Group | |
| 1.2.1.44 | 5.33 | - |
4-coumaroyl-CoA | isoform CCR20, at pH 6.3 and 30°C | Oryza sativa Japonica Group | |
| 1.2.1.44 | 7.17 | - |
feruloyl-CoA | isoform CCR19, at pH 6.3 and 30°C | Oryza sativa Japonica Group | |
| 1.2.1.44 | 9.17 | - |
sinapoyl-CoA | isoform CCR19, at pH 6.3 and 30°C | Oryza sativa Japonica Group | |
| 1.2.1.44 | 10 | - |
4-coumaroyl-CoA | isoform CCR19, at pH 6.3 and 30°C | Oryza sativa Japonica Group | |
| 1.2.1.44 | 12.8 | - |
feruloyl-CoA | isoform CCR21, at pH 6.3 and 30°C | Oryza sativa Japonica Group | |
| 1.2.1.44 | 23.5 | - |
feruloyl-CoA | isoform CCR20, at pH 6.3 and 30°C | Oryza sativa Japonica Group | |
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