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Literature summary extracted from

  • Bowsher, R.R.; Henry, D.P.
    Purification, characterization and identification of rat brain cytosolic tyrosine transaminase as glutamine transaminase-K (2020), Neurochem. Int., 133, 104653 .
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.6.1.64 cytosol
-
 Rattus norvegicus 5829
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.6.1.64 L-glutamine + phenylpyruvate Rattus norvegicus
-
 2-oxoglutaramate + L-phenylalanine
-
 ?
2.6.1.64 L-glutamine + phenylpyruvate Rattus norvegicus Wistar
-
 2-oxoglutaramate + L-phenylalanine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.64 Rattus norvegicus
-
-
-
2.6.1.64 Rattus norvegicus Wistar
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.6.1.64 native enzyme from rat brain by ultracentrifugation at 220000 x g, followed by ammonium sulfate fractionation, hydropbobic interaction chromatography, anion exchange chromatography, and hydroxyapatite chromatography Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.6.1.64 brain
-
 Rattus norvegicus
-
2.6.1.64 cerebellum
-
 Rattus norvegicus
-
2.6.1.64 cerebral cortex
-
 Rattus norvegicus
-
2.6.1.64 corpus striatum
-
 Rattus norvegicus
-
2.6.1.64 hypothalamus
-
 Rattus norvegicus
-
2.6.1.64 medulla oblongata
-
 Rattus norvegicus
-
2.6.1.64 midbrain
-
 Rattus norvegicus
-
2.6.1.64 pons
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.64 L-glutamine + phenylpyruvate
-
 Rattus norvegicus 2-oxoglutaramate + L-phenylalanine
-
 ?
2.6.1.64 L-glutamine + phenylpyruvate
-
 Rattus norvegicus Wistar 2-oxoglutaramate + L-phenylalanine
-
 ?
2.6.1.64 additional information analysis of the enzyme's substrate and 2-oxoacid cosubstrate specificities. Differentiation of the enzyme activity from tyrosine transaminase, EC 2.6.1.5, detailed overview Rattus norvegicus ?
-
-
2.6.1.64 additional information analysis of the enzyme's substrate and 2-oxoacid cosubstrate specificities. Differentiation of the enzyme activity from tyrosine transaminase, EC 2.6.1.5, detailed overview Rattus norvegicus Wistar ?
-
-

Synonyms

EC Number Synonyms Comment Organism
2.6.1.64 Gln/phenylpyruvate transaminase
-
 Rattus norvegicus
2.6.1.64 glutamine transaminase-K
-
 Rattus norvegicus
2.6.1.64 glutamine/phenylpyruvate transaminase
-
 Rattus norvegicus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.6.1.64 37
-
 assay at Rattus norvegicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.6.1.64 8.5
-
 assay at Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
2.6.1.64 pyridoxal 5'-phosphate
-
 Rattus norvegicus