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Literature summary extracted from

  • Nambiar, D.; Sharma, O.; Duff, M.R.; Howell, E.E.
    Effects of osmolytes on ligand binding to dihydropteroate synthase from Bacillus anthracis (2020), J. Phys. Chem. B, 124, 6212-6224 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.5.1.15 expression in Escherichia coli BL21 Bacillus anthracis

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.5.1.15 additional information the association rates of pterin diphosphate are mostly unaffected by the osmolytes, except for a 2fold decrease in the presence of 1 M trehalose Bacillus anthracis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.5.1.15 (7,8-dihydropterin-6-yl)methyl diphosphate + 4-aminobenzoate Bacillus anthracis
-
 diphosphate + 7,8-dihydropteroate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.15 Bacillus anthracis
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.5.1.15
-
 Bacillus anthracis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.15 (7,8-dihydropterin-6-yl)methyl diphosphate + 4-aminobenzoate
-
 Bacillus anthracis diphosphate + 7,8-dihydropteroate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.5.1.15 DHPS
-
 Bacillus anthracis