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Literature summary extracted from

  • Wang, C.; Zheng, L.; Tang, Z.; Sun, S.; Ma, J.F.; Huang, X.Y.; Zhao, F.J.
    OASTL-A1 functions as a cytosolic cysteine synthase and affects arsenic tolerance in rice (2020), J. Exp. Bot., 71, 3678-3689 .
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.5.1.47 2.3
-
hydrogen sulfide pH 7.5, 25°C Oryza sativa Japonica Group
2.5.1.47 3.8
-
O-acetyl-L-Ser pH 7.5, 25°C Oryza sativa Japonica Group

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.5.1.47 cytosol
-
Oryza sativa Japonica Group 5829
-

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.47 Oryza sativa Japonica Group Q9XEA8
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.5.1.47 node expressed at the reproductive stage Oryza sativa Japonica Group
-
2.5.1.47 root expressed in roots at the vegetative growth stage, expressed in the outer cortex and the vascular cylinder in the root mature zone Oryza sativa Japonica Group
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.47 O-acetyl-L-Ser + hydrogen sulfide
-
Oryza sativa Japonica Group L-Cys + acetate
-
?

Subunits

EC Number Subunits Comment Organism
2.5.1.47 ? x * 35100, SDS-PAGE, recombinant protein Oryza sativa Japonica Group

Synonyms

EC Number Synonyms Comment Organism
2.5.1.47 OASTL-A1
-
Oryza sativa Japonica Group
2.5.1.47 Os03g53650
-
Oryza sativa Japonica Group
2.5.1.47 RCS3
-
Oryza sativa Japonica Group

Expression

EC Number Organism Comment Expression
2.5.1.47 Oryza sativa Japonica Group expression in roots is strongly induced by As exposure up

General Information

EC Number General Information Comment Organism
2.5.1.47 physiological function knockout of OASTL-A1 leads to significantly lower levels of cysteine, glutathione, and phytochelatins in roots and increased sensitivity to arsenate stress. The knockout reduces As accumulation in the roots, but increases As accumulation in shoots. OASTL-A1 is able to complement an Escherichia coli cysteine synthase-deficient mutant Oryza sativa Japonica Group