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Literature summary extracted from

  • Wang, H.; Wang, C.; Fan, W.; Yang, J.; Appelhagen, I.; Wu, Y.; Zhang, P.
    A novel glycosyltransferase catalyses the transfer of glucose to glucosylated anthocyanins in purple sweet potato (2018), J. Exp. Bot., 69, 5444-5459 .
    View publication on PubMedView publication on EuropePMC

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
2.4.1.297 molecular docking studies. Residues Thr22/Ser276/Glu360/Gln337/Gln338/Trp334 form a binding pocket and interact with the uridine group of UDP-glucose. Glu277/His352/Ser357 show strong interactions with the diphosphate group Ipomoea batatas

Protein Variants

EC Number Protein Variants Comment Organism
2.4.1.297 T138I no activity with substrates UDP-alpha-D-glucose + cyanidin 3-O-beta-D-glucoside Ipomoea batatas

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.297 cytosol
-
 Ipomoea batatas 5829
-

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.297 Ipomoea batatas
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.297 additional information no acceptor substrates: cyanidin, cyanidin 3,5-O-diglucoside, and flavonol 3-O-glucoside. No donors: UDP-xylose, UDP-galactose, and UDP-arabinose Ipomoea batatas ?
-
-
2.4.1.297 UDP-alpha-D-glucose + cyanidin 3-O-beta-D-glucoside
-
 Ipomoea batatas UDP + cyanidin 3-O-sophoroside
-
 ?
2.4.1.297 UDP-alpha-D-glucose + peonidin 3-O-beta-D-glucoside
-
 Ipomoea batatas UDP + peonidin 3-O-sophoroside
-
 ?
2.4.1.297 UDP-alpha-D-xylose + cyanidin 3-O-beta-D-glucoside
-
 Ipomoea batatas UDP + cyanidin 3-O-glucosyl-2''-O-alpha-D-xyloside
-
 ?

Expression

EC Number Organism Comment Expression
2.4.1.297 Ipomoea batatas 3GGT expression is associated with anthocyanin accumulation in different tissues during Ipomea batatas plant development and is regulated by the transcription factor IbMYB1 additional information

General Information

EC Number General Information Comment Organism
2.4.1.297 physiological function wild-type and ugt79b1 mutants (defective in UDP carbohydrate-dependent glycosyltransferases) of Arabidopsis plants overexpressing 3GGT produce cyanidin 3-O-sophoroside Ipomoea batatas