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Literature summary extracted from

  • Korboukh, V.; Li, N.; Barr, E.; Bollinger Jr., J.; Krebs, C.
    A long-lived, substrate-hydroxylating peroxodiiron(III/III) intermediate in the amine oxygenase, AurF, from Streptomyces thioluteus (2009), J. Am. Chem. Soc., 131, 13608-13609 .
    View publication on PubMedView publication on EuropePMC

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.14.99.68 Iron the Fe2 II/II cluster in AurF reacts with O2 in the absence of substrate to form a stable (half-life of about 7 min at 20°C) adduct with spectroscopic properties characteristic of a peroxo-Fe2 III/III complex Streptomyces thioluteus

Organism

EC Number Organism UniProt Comment Textmining
1.14.99.68 Streptomyces thioluteus Q70KH9
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-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.99.68 4-aminobenzoate + reduced acceptor + 2 O2
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 Streptomyces thioluteus 4-nitrobenzoate + acceptor + 2 H2O
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 ?

General Information

EC Number General Information Comment Organism
1.14.99.68 physiological function the Fe2 II/II cluster in AurF reacts with O2 in the absence of substrate to form a stable (half-life of about 7 min at 20°C) adduct with spectroscopic properties characteristic of a peroxo-Fe2 III/III complex. The intermediate complex decays rapidly (half-life of about 0.005 s at 20°C) when mixed with stoichiometric 4-aminobenzoate. Over 80% conversion of 4-aminobenzoate to 4-nitrobenzoate is observed upon addition of less than 0.3 equivalents of the amine substrate to a solution of the intermediate peroxo-Fe2 III/III complex. The complex might effect all three steps in the sequence Streptomyces thioluteus