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Literature summary extracted from

  • Takeuchi, H.; Fernandez-Valdivia, R.; Caswell, D.; Nita-Lazar, A.; Rana, N.; Garner, T.; Weldeghiorghis, T.; Macnaughtan, M.; Jafar-Nejad, H.; Haltiwanger, R.
    Rumi functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase (2011), Proc. Natl. Acad. Sci. USA, 108, 16600-16605 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.1.376 expressed in Drosophila melanogaster mutant clones Mus musculus
2.4.1.376 expressed in Drosophila melanogaster mutant clones Homo sapiens
2.4.2.63 expressed in Drosophila melanogaster mutant clones Mus musculus
2.4.2.63 expressed in Drosophila melanogaster mutant clones Homo sapiens

Protein Variants

EC Number Protein Variants Comment Organism
2.4.1.376 G169E inactive Mus musculus
2.4.2.63 G169E inactive Mus musculus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.376 Mn2+ 10 mM used in assay conditions Mus musculus
2.4.2.63 Mn2+ 10 mM used in assay conditions Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.376 additional information Mus musculus the enzyme functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase ?
-
-
2.4.1.376 additional information Homo sapiens the enzyme functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase ?
-
-
2.4.1.376 UDP-alpha-D-glucose + [factor VII protein with EGF-like domain]-L-serine Mus musculus highest activity UDP + [factor VII protein with EGF-like domain]-3-O-(beta-D-glucosyl)-L-serine
-
 ?
2.4.1.376 UDP-alpha-D-glucose + [factor VII protein with EGF-like domain]-L-serine Homo sapiens highest activity UDP + [factor VII protein with EGF-like domain]-3-O-(beta-D-glucosyl)-L-serine
-
 ?
2.4.2.63 additional information Mus musculus the enzyme functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase ?
-
-
2.4.2.63 additional information Homo sapiens the enzyme functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase ?
-
-
2.4.2.63 UDP-alpha-D-xylose + [factor VII protein with EGF-like domain]-L-serine Mus musculus
-
 UDP + [factor VII protein with EGF-like domain]-3-O-(beta-D-xylosyl)-L-serine
-
 ?
2.4.2.63 UDP-alpha-D-xylose + [factor VII protein with EGF-like domain]-L-serine Homo sapiens
-
 UDP + [factor VII protein with EGF-like domain]-3-O-(beta-D-xylosyl)-L-serine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.376 Homo sapiens
-
-
-
2.4.1.376 Mus musculus
-
-
-
2.4.2.63 Homo sapiens
-
-
-
2.4.2.63 Mus musculus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.376 additional information the enzyme functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase Mus musculus ?
-
-
2.4.1.376 additional information the enzyme functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase Homo sapiens ?
-
-
2.4.1.376 UDP-alpha-D-glucose + [factor VII protein with EGF-like domain]-L-serine highest activity Mus musculus UDP + [factor VII protein with EGF-like domain]-3-O-(beta-D-glucosyl)-L-serine
-
 ?
2.4.1.376 UDP-alpha-D-glucose + [factor VII protein with EGF-like domain]-L-serine highest activity Homo sapiens UDP + [factor VII protein with EGF-like domain]-3-O-(beta-D-glucosyl)-L-serine
-
 ?
2.4.2.63 additional information the enzyme functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase Mus musculus ?
-
-
2.4.2.63 additional information the enzyme functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase Homo sapiens ?
-
-
2.4.2.63 UDP-alpha-D-xylose + [factor VII protein with EGF-like domain]-L-serine
-
 Mus musculus UDP + [factor VII protein with EGF-like domain]-3-O-(beta-D-xylosyl)-L-serine
-
 ?
2.4.2.63 UDP-alpha-D-xylose + [factor VII protein with EGF-like domain]-L-serine
-
 Homo sapiens UDP + [factor VII protein with EGF-like domain]-3-O-(beta-D-xylosyl)-L-serine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.376 Poglut
-
 Mus musculus
2.4.1.376 Poglut
-
 Homo sapiens
2.4.1.376 Rumi
-
 Mus musculus
2.4.1.376 Rumi
-
 Homo sapiens
2.4.2.63 Poglut
-
 Mus musculus
2.4.2.63 Poglut
-
 Homo sapiens
2.4.2.63 Rumi
-
 Mus musculus
2.4.2.63 Rumi
-
 Homo sapiens