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Literature summary extracted from

  • Itoh, H.; Matsui, M.; Miyamura, Y.; Takeda, I.; Ishii, J.; Kumagai, T.; Machida, M.; Shibata, T.; Arita, M.
    Biosynthesis of novel statins by combining heterologous genes from Xylaria and Aspergillus (2018), ACS Synth. Biol., 7, 2783-2789 .
    View publication on PubMed

Application

EC Number Application Comment Organism
2.3.1.244 synthesis using a multivector expression system in Saccharomyces cerevisiae, two natural statins from two fungal species, i.e., lovastatin from Aspergillus terreus and FR901512 from Xylaria grammica are reconstituted, but also new statin structures by mixing their genes Aspergillus terreus

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.244 Aspergillus terreus Q9Y7D5
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Synonyms

EC Number Synonyms Comment Organism
2.3.1.244 LovF
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Aspergillus terreus