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Literature summary extracted from

  • Zouaz, A.; Fernando, C.; Perez, Y.; Sardet, C.; Julien, E.; Grimaud, C.
    Cell-cycle regulation of non-enzymatic functions of the Drosophila methyltransferase PR-Set7 (2018), Nucleic Acids Res., 46, 2834-2849 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.1.1.361 expressed in S2 cells Drosophila melanogaster

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.1.1.361 nucleosome
-
 Drosophila melanogaster 786
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.1.1.361 additional information Drosophila melanogaster the proteolytic degradation of the enzyme is controlled by the SCFSlimb ligase complex ?
-
 ?
2.1.1.361 S-adenosyl-L-methionine + a [histone H4]-L-lysine20 Drosophila melanogaster
-
 S-adenosyl-L-homocysteine + a [histone H4]-N6-methyl-L-lysine20
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.361 Drosophila melanogaster Q9VFK6
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.1.1.361 phosphoprotein column chromatography Drosophila melanogaster

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.361 additional information the proteolytic degradation of the enzyme is controlled by the SCFSlimb ligase complex Drosophila melanogaster ?
-
 ?
2.1.1.361 S-adenosyl-L-methionine + a [histone H4]-L-lysine20
-
 Drosophila melanogaster S-adenosyl-L-homocysteine + a [histone H4]-N6-methyl-L-lysine20
-
 ?

Subunits

EC Number Subunits Comment Organism
2.1.1.361 ? x * 100000, SDS-PAGE Drosophila melanogaster

Synonyms

EC Number Synonyms Comment Organism
2.1.1.361 histone H4-K20 methyltransferase
-
 Drosophila melanogaster
2.1.1.361 KMT5a
-
 Drosophila melanogaster
2.1.1.361 Pr-Set7
-
 Drosophila melanogaster
2.1.1.361 SET8
-
 Drosophila melanogaster
2.1.1.361 SETD8
-
 Drosophila melanogaster

General Information

EC Number General Information Comment Organism
2.1.1.361 physiological function Slimb-mediated enzyme proteolysis is a critical regulatory mechanism required for proper interphase chromatin organization at G1/S transition Drosophila melanogaster