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Literature summary extracted from

  • Tayyrov, A.; Azevedo, S.; Herzog, R.; Vogt, E.; Arzt, S.; Luethy, P.; Mueller, P.; Ruehl, M.; Hennicke, F.; Kuenzler, M.
    Heterologous production and functional characterization of ageritin, a novel type of ribotoxin highly expressed during fruiting of the edible mushroom Agrocybe aegerita (2019), Appl. Environ. Microbiol., 85, e01549 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.6.1.23 expression in Escherichia coli Cyclocybe aegerita

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.6.1.23 cytoplasm sequence lacks a signal peptide for classical secretion Cyclocybe aegerita 5737
-

Organism

EC Number Organism UniProt Comment Textmining
4.6.1.23 Cyclocybe aegerita C0HLG3
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.6.1.23 rabbit 28S rRNA containing guanosine-adenosine pair + H2O
-
 Cyclocybe aegerita an [RNA fragment]-3'-adenosine-3'-phosphate + a 5'-a hydroxy-guanosine-3'-[RNA fragment]
-
 ?
4.6.1.23 rabbit ribosomes + H2O ribosomes isolated from reticulocyte lysate Cyclocybe aegerita ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.6.1.23 AGT1
-
 Cyclocybe aegerita

Expression

EC Number Organism Comment Expression
4.6.1.23 Cyclocybe aegerita expression is highly induced during fruiting up

General Information

EC Number General Information Comment Organism
4.6.1.23 physiological function ageritin heterologously expressed in Escherichia coli shows a strong toxicity against Aedes aegypti larvae yet not against nematodes. Entomotoxicity of ageritin is mediated by ribonucleolytic cleavage Cyclocybe aegerita