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Literature summary extracted from
- DNA target recognition domains in the type I restriction and modification systems of Staphylococcus aureus (2017), Nucleic Acids Res., 45, 3395-3406 .
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 3.1.21.3 | expression in Escherichia coli | Staphylococcus aureus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.21.3 | Staphylococcus aureus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.1.21.3 | expression in Escherichia coli | Staphylococcus aureus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.21.3 | additional information | determination of target sequences recognized by the Sau1 Type I RM systems present in a wide range of the most prevalent Staphylococcus aureus lineages and assigned the sequences recognized to particular target recognition domains within the RM enzymes | Staphylococcus aureus | ? | - |
? |  |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.1.21.3 | Sau1 | type I restriction and modification system | Staphylococcus aureus |
| 3.1.21.3 | Sau1 Type I RM system | - |
Staphylococcus aureus |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 3.1.21.3 | evolution | Staphylococcus aureus displays a clonal population structure in which horizontal gene transfer between different lineages is extremely rare. This is due, in part, to the presence of a Type I DNA restriction-modification (RM) system given the generic name of Sau1, which maintains different patterns of methylation on specific target sequences on the genomes of different lineages. The determination of so many recognition sequences of Type I RM systems in different lineages of Staphylococcus aureus, means that now the population structure of Staphylococcus aureus can be investigated from an epigenetic/evolutionary perspective | Staphylococcus aureus |
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Release 2023.1 (January 2023)
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