Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Snoberger, A.; Brettrager, E.; Smith, D.
    Conformational switching in the coiled-coil domains of a proteasomal ATPase regulates substrate processing (2018), Nat. Commun., 9, 2374 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.6.1.5 expressed in Escherichia coli BL21-DE3-RIL cells Methanocaldococcus jannaschii

Protein Variants

EC Number Protein Variants Comment Organism
5.6.1.5 M87A the mutant shows almost wild type activity Methanocaldococcus jannaschii

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.6.1.5 ATP + H2O + polypeptide Methanocaldococcus jannaschii
-
 ADP + phosphate + unfolded polypeptide
-
 ?
5.6.1.5 ATP + H2O + polypeptide Methanocaldococcus jannaschii ATCC 43067
-
 ADP + phosphate + unfolded polypeptide
-
 ?
5.6.1.5 CTP + H2O + polypeptide Methanocaldococcus jannaschii
-
 CDP + phosphate + unfolded polypeptide
-
 ?
5.6.1.5 CTP + H2O + polypeptide Methanocaldococcus jannaschii ATCC 43067
-
 CDP + phosphate + unfolded polypeptide
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.6.1.5 Methanocaldococcus jannaschii Q58576
-
-
5.6.1.5 Methanocaldococcus jannaschii ATCC 43067 Q58576
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
5.6.1.5 HiTrap Q column chromatography and Superose 12 gel filtration Methanocaldococcus jannaschii

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.6.1.5 ATP + H2O + polypeptide
-
 Methanocaldococcus jannaschii ADP + phosphate + unfolded polypeptide
-
 ?
5.6.1.5 ATP + H2O + polypeptide
-
 Methanocaldococcus jannaschii ATCC 43067 ADP + phosphate + unfolded polypeptide
-
 ?
5.6.1.5 ATP + H2O + polypeptide GFPssrA
-
 Methanocaldococcus jannaschii ADP + phosphate + unfolded polypeptide GFPssrA
-
 ?
5.6.1.5 ATP + H2O + polypeptide GFPssrA
-
 Methanocaldococcus jannaschii ATCC 43067 ADP + phosphate + unfolded polypeptide GFPssrA
-
 ?
5.6.1.5 CTP + H2O + polypeptide
-
 Methanocaldococcus jannaschii CDP + phosphate + unfolded polypeptide
-
 ?
5.6.1.5 CTP + H2O + polypeptide
-
 Methanocaldococcus jannaschii ATCC 43067 CDP + phosphate + unfolded polypeptide
-
 ?

Subunits

EC Number Subunits Comment Organism
5.6.1.5 homohexamer
-
 Methanocaldococcus jannaschii

Synonyms

EC Number Synonyms Comment Organism
5.6.1.5 AAA+ ATPase
-
 Methanocaldococcus jannaschii
5.6.1.5 PAN
-
 Methanocaldococcus jannaschii
5.6.1.5 proteasomal ATPase
-
 Methanocaldococcus jannaschii
5.6.1.5 Rpt1 subunit Methanocaldococcus jannaschii
5.6.1.5 Rpt2 subunit Methanocaldococcus jannaschii
5.6.1.5 Rpt3 subunit Methanocaldococcus jannaschii
5.6.1.5 Rpt4 subunit Methanocaldococcus jannaschii
5.6.1.5 Rpt5 subunit Methanocaldococcus jannaschii
5.6.1.5 Rpt6 subunit Methanocaldococcus jannaschii