EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.4.52 | Pseudomonas putida | - |
- |
- |
3.1.4.52 | Pseudomonas putida KT2442 | - |
- |
- |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.1.4.52 | BifA | - |
Pseudomonas putida |
EC Number | General Information | Comment | Organism |
---|---|---|---|
3.1.4.52 | physiological function | a bifA mutant displays increased biofilm and pellicle formation, cell aggregation in liquid medium and decreased starvation-induced biofilm dispersal relative to the wild type. The mutation does not affect swarming motility. The hyperadherent phenotype of the mutant correlates with a general increase in cyclic diguanylate levels, Congo Red-binding exopolysaccharide production and transcription of the adhesin-encoding lapA gene. Integrity of the EAL motif and a modified GGDEF motif are crucial for BifA activity. c-Di-GMP depletion by overexpression of a heterologous cyclic di-GMP phosphodiesterase in the mutant restores wild-type biofilm dispersal and lapA expression | Pseudomonas putida |