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Literature summary extracted from

  • Mueller, M.; He, J.; Hertweck, C.
    Dissection of the late steps in aureothin biosynthesis (2006), ChemBioChem, 7, 37-39 .
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.1.1.353 S-adenosyl-L-methionine + demethylluteothin Streptomyces thioluteus
-
 S-adenosyl-L-homocysteine + luteothin
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.353 Streptomyces thioluteus Q70KH3
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.353 S-adenosyl-L-methionine + demethylluteothin
-
 Streptomyces thioluteus S-adenosyl-L-homocysteine + luteothin
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.353 AurI
-
 Streptomyces thioluteus
2.1.1.353 gamma-pyrone methyltransferase
-
 Streptomyces thioluteus

General Information

EC Number General Information Comment Organism
2.1.1.353 physiological function in aureothin biosynthesis, methyltransferase AurI transfers the SAM methyl onto the alpha-hydroxyl group of the pyrone ring of demethylluteothin i.e. nordeoxyaureothin, to yield luteothin, i.e. deoxyaureothin Streptomyces thioluteus