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Literature summary extracted from

  • Shaheen, A.; Iqbal, M.; Mirza, O.; Rahman, M.
    Structural biology meets drug resistance an overview on multidrug resistance transporters (2017), J. Indian Inst. Sci., 97, 165-175 .
No PubMed abstract available

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
7.6.2.2 plasma membrane
-
 Staphylococcus aureus 5886
-
7.6.2.2 plasma membrane
-
 Bacillus subtilis 5886
-
7.6.2.2 plasma membrane
-
 Mus musculus 5886
-
7.6.2.2 plasma membrane
-
 Pseudomonas aeruginosa 5886
-
7.6.2.2 plasma membrane
-
 Salmonella enterica 5886
-
7.6.2.2 plasma membrane
-
 Escherichia coli 5886
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7.6.2.2 ATP + H2O + xenobiotic[side 1] Staphylococcus aureus
-
 ADP + phosphate + xenobiotic[side 2]
-
 ?
7.6.2.2 ATP + H2O + xenobiotic[side 1] Bacillus subtilis
-
 ADP + phosphate + xenobiotic[side 2]
-
 ?
7.6.2.2 ATP + H2O + xenobiotic[side 1] Mus musculus
-
 ADP + phosphate + xenobiotic[side 2]
-
 ?
7.6.2.2 ATP + H2O + xenobiotic[side 1] Pseudomonas aeruginosa
-
 ADP + phosphate + xenobiotic[side 2]
-
 ?
7.6.2.2 ATP + H2O + xenobiotic[side 1] Salmonella enterica
-
 ADP + phosphate + xenobiotic[side 2]
-
 ?
7.6.2.2 ATP + H2O + xenobiotic[side 1] Escherichia coli
-
 ADP + phosphate + xenobiotic[side 2]
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
7.6.2.2 Bacillus subtilis
-
-
-
7.6.2.2 Escherichia coli P0AEY8
-
-
7.6.2.2 Mus musculus
-
-
-
7.6.2.2 Pseudomonas aeruginosa
-
-
-
7.6.2.2 Salmonella enterica
-
-
-
7.6.2.2 Staphylococcus aureus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.6.2.2 ATP + H2O + xenobiotic[side 1]
-
 Staphylococcus aureus ADP + phosphate + xenobiotic[side 2]
-
 ?
7.6.2.2 ATP + H2O + xenobiotic[side 1]
-
 Bacillus subtilis ADP + phosphate + xenobiotic[side 2]
-
 ?
7.6.2.2 ATP + H2O + xenobiotic[side 1]
-
 Mus musculus ADP + phosphate + xenobiotic[side 2]
-
 ?
7.6.2.2 ATP + H2O + xenobiotic[side 1]
-
 Pseudomonas aeruginosa ADP + phosphate + xenobiotic[side 2]
-
 ?
7.6.2.2 ATP + H2O + xenobiotic[side 1]
-
 Salmonella enterica ADP + phosphate + xenobiotic[side 2]
-
 ?
7.6.2.2 ATP + H2O + xenobiotic[side 1]
-
 Escherichia coli ADP + phosphate + xenobiotic[side 2]
-
 ?

Synonyms

EC Number Synonyms Comment Organism
7.6.2.2 ABC multidrug efflux transporter
-
 Staphylococcus aureus
7.6.2.2 ABC multidrug efflux transporter
-
 Bacillus subtilis
7.6.2.2 ABC multidrug efflux transporter
-
 Mus musculus
7.6.2.2 ABC multidrug efflux transporter
-
 Pseudomonas aeruginosa
7.6.2.2 ABC multidrug efflux transporter
-
 Salmonella enterica
7.6.2.2 ABC multidrug efflux transporter
-
 Escherichia coli
7.6.2.2 AcrB
-
 Pseudomonas aeruginosa
7.6.2.2 AcrB
-
 Salmonella enterica
7.6.2.2 acriflavine resistance protein
-
 Pseudomonas aeruginosa
7.6.2.2 acriflavine resistance protein
-
 Salmonella enterica
7.6.2.2 Bmr
-
 Bacillus subtilis
7.6.2.2 MdfA
-
 Escherichia coli
7.6.2.2 MDR transporter
-
 Staphylococcus aureus
7.6.2.2 MDR transporter
-
 Bacillus subtilis
7.6.2.2 MDR transporter
-
 Mus musculus
7.6.2.2 MDR transporter
-
 Pseudomonas aeruginosa
7.6.2.2 MDR transporter
-
 Salmonella enterica
7.6.2.2 MDR transporter
-
 Escherichia coli
7.6.2.2 multidrug resistance transporter
-
 Staphylococcus aureus
7.6.2.2 multidrug resistance transporter
-
 Bacillus subtilis
7.6.2.2 multidrug resistance transporter
-
 Mus musculus
7.6.2.2 multidrug resistance transporter
-
 Pseudomonas aeruginosa
7.6.2.2 multidrug resistance transporter
-
 Salmonella enterica
7.6.2.2 multidrug resistance transporter
-
 Escherichia coli
7.6.2.2 P-glycoprotein
-
 Mus musculus
7.6.2.2 P-gp
-
 Mus musculus
7.6.2.2 Sav1886
-
 Staphylococcus aureus