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Literature summary extracted from

  • Albert, A.; Tiwari, V.; Paul, E.; Ganesan, D.; Ayyavu, M.; Kujur, R.; Ponnusamy, S.; Shanmugam, K.; Saso, L.; Govindan Sadasivam, S.
    Expression of heterologous oxalate decarboxylase in HEK293 cells confers protection against oxalate induced oxidative stress as a therapeutic approach for calcium oxalate stone disease (2017), J. Enzyme Inhib. Med. Chem., 32, 426-433 .
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
4.1.1.2 medicine HEK-293 cells expressing the enzyme capable of degrading oxalate protect cells from oxidative damage and thus serve as a therapeutic option for prevention of calcium oxalate stone disease Bacillus subtilis

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.1.1.2 expressed in HEK-293 cells Bacillus subtilis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.2 oxalate + H+ Bacillus subtilis
-
 formate + CO2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.2 Bacillus subtilis
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.2 oxalate + H+
-
 Bacillus subtilis formate + CO2
-
 ?

Subunits

EC Number Subunits Comment Organism
4.1.1.2 ? x * 44000, SDS-PAGE Bacillus subtilis

Synonyms

EC Number Synonyms Comment Organism
4.1.1.2 OXDC
-
 Bacillus subtilis
4.1.1.2 YvrK
-
 Bacillus subtilis