Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Kumari, I.; Chaudhary, N.; Sandhu, P.; Ahmed, M.; Akhter, Y.
    Structural and mechanistic analysis of engineered trichodiene synthase enzymes from Trichoderma harzianum towards higher catalytic activities empowering sustainable agriculture (2016), J. Biomol. Struct. Dyn., 34, 1176-1189 .
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
4.2.3.6 D109E the mutant with increased activity shows more stability than the wild type enzyme, an increased number of electrostatic interactions and better binding energies with the ligand Trichoderma harzianum
4.2.3.6 D109E/D248Y the mutant with increased activity shows more stability than the wild type enzyme, an increased number of electrostatic interactions and better binding energies with the ligand Trichoderma harzianum
4.2.3.6 D248Y the mutant with increased activity shows more stability than the wild type enzyme, an increased number of electrostatic interactions and better binding energies with the ligand Trichoderma harzianum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.2.3.6 (2E,6E)-farnesyl diphosphate Trichoderma harzianum
-
 trichodiene + diphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.2.3.6 Trichoderma harzianum
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.3.6 (2E,6E)-farnesyl diphosphate
-
 Trichoderma harzianum trichodiene + diphosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.2.3.6 tri5
-
 Trichoderma harzianum