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Literature summary extracted from

  • Gan, K.; Sankaran, K.; Williams, M.G.; Aldea, M.; Rudd, K.E.; Kushner, S.R.; Wu, H.C.
    The umpA gene of Escherichia coli encodes phosphatidylglycerol prolipoprotein diacylglyceryl transferase (lgt) and regulates thymidylate synthase levels through translational coupling (1995), J. Bacteriol., 177, 1879-1882 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.5.1.145 expressed in Escherichia coli strains SK634, SK635, and SK636 Salmonella enterica subsp. enterica serovar Typhimurium
2.5.1.145 expressed in Salmonella typhimurium strain SE5221 Escherichia coli

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.5.1.145 membrane
-
 Salmonella enterica subsp. enterica serovar Typhimurium 16020
-
2.5.1.145 membrane
-
 Escherichia coli 16020
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.5.1.145 L-1-phosphatidyl-sn-glycerol + a [prolipoprotein]-L-cysteine Salmonella enterica subsp. enterica serovar Typhimurium
-
 sn-glycerol 1-phosphate + an [prolipoprotein]-S-1,2-diacyl-sn-glyceryl-L-cysteine
-
 ?
2.5.1.145 L-1-phosphatidyl-sn-glycerol + a [prolipoprotein]-L-cysteine Escherichia coli
-
 sn-glycerol 1-phosphate + an [prolipoprotein]-S-1,2-diacyl-sn-glyceryl-L-cysteine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.145 Escherichia coli P60955
-
-
2.5.1.145 Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.145 L-1-phosphatidyl-sn-glycerol + a [prolipoprotein]-L-cysteine
-
 Salmonella enterica subsp. enterica serovar Typhimurium sn-glycerol 1-phosphate + an [prolipoprotein]-S-1,2-diacyl-sn-glyceryl-L-cysteine
-
 ?
2.5.1.145 L-1-phosphatidyl-sn-glycerol + a [prolipoprotein]-L-cysteine
-
 Escherichia coli sn-glycerol 1-phosphate + an [prolipoprotein]-S-1,2-diacyl-sn-glyceryl-L-cysteine
-
 ?

Subunits

EC Number Subunits Comment Organism
2.5.1.145 ? x * 26000, SDS-PAGE Salmonella enterica subsp. enterica serovar Typhimurium
2.5.1.145 ? x * 26000, SDS-PAGE Escherichia coli

Synonyms

EC Number Synonyms Comment Organism
2.5.1.145 LGT
-
 Salmonella enterica subsp. enterica serovar Typhimurium
2.5.1.145 phosphatidylglycerol:prolipoprotein diacylglyceryl transferase
-
 Salmonella enterica subsp. enterica serovar Typhimurium
2.5.1.145 phosphatidylglycerol:prolipoprotein diacylglyceryl transferase
-
 Escherichia coli
2.5.1.145 umpA
-
 Escherichia coli

General Information

EC Number General Information Comment Organism
2.5.1.145 physiological function the enzyme is essential for the viability Salmonella enterica subsp. enterica serovar Typhimurium
2.5.1.145 physiological function the enzyme is essential for the viability Escherichia coli