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Literature summary extracted from

  • Sorci, L.; Ruggieri, S.; Raffaelli, N.
    NAD homeostasis in the bacterial response to DNA/RNA damage (2014), DNA Repair, 23, 17-26 .
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.5.1.2 NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m Gluconobacter oxydans
-
 (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide
-
 ?
6.5.1.2 NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m Desulfovibrio vulgaris
-
 (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide
-
 ?
6.5.1.2 NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m Thermotoga maritima
-
 (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide
-
 ?
6.5.1.2 NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m Syntrophotalea carbinolica
-
 (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide
-
 ?
6.5.1.2 NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m Oleidesulfovibrio alaskensis
-
 (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide
-
 ?
6.5.1.2 NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m Synechococcus elongatus
-
 (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide
-
 ?
6.5.1.2 NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m Lawsonia intracellularis
-
 (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.5.1.2 Desulfovibrio vulgaris
-
-
-
6.5.1.2 Gluconobacter oxydans
-
-
-
6.5.1.2 Lawsonia intracellularis
-
-
-
6.5.1.2 Oleidesulfovibrio alaskensis
-
-
-
6.5.1.2 Synechococcus elongatus
-
-
-
6.5.1.2 Syntrophotalea carbinolica
-
-
-
6.5.1.2 Thermotoga maritima
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.5.1.2 NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m
-
 Gluconobacter oxydans (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide
-
 ?
6.5.1.2 NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m
-
 Desulfovibrio vulgaris (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide
-
 ?
6.5.1.2 NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m
-
 Thermotoga maritima (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide
-
 ?
6.5.1.2 NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m
-
 Syntrophotalea carbinolica (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide
-
 ?
6.5.1.2 NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m
-
 Oleidesulfovibrio alaskensis (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide
-
 ?
6.5.1.2 NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m
-
 Synechococcus elongatus (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide
-
 ?
6.5.1.2 NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m
-
 Lawsonia intracellularis (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.5.1.2 LigA
-
 Gluconobacter oxydans
6.5.1.2 LigA
-
 Desulfovibrio vulgaris
6.5.1.2 LigA
-
 Thermotoga maritima
6.5.1.2 LigA
-
 Syntrophotalea carbinolica
6.5.1.2 LigA
-
 Oleidesulfovibrio alaskensis
6.5.1.2 LigA
-
 Synechococcus elongatus
6.5.1.2 LigA
-
 Lawsonia intracellularis
6.5.1.2 NAD-dependent DNA ligase
-
 Gluconobacter oxydans
6.5.1.2 NAD-dependent DNA ligase
-
 Desulfovibrio vulgaris
6.5.1.2 NAD-dependent DNA ligase
-
 Thermotoga maritima
6.5.1.2 NAD-dependent DNA ligase
-
 Syntrophotalea carbinolica
6.5.1.2 NAD-dependent DNA ligase
-
 Oleidesulfovibrio alaskensis
6.5.1.2 NAD-dependent DNA ligase
-
 Synechococcus elongatus
6.5.1.2 NAD-dependent DNA ligase
-
 Lawsonia intracellularis

Cofactor

EC Number Cofactor Comment Organism Structure
6.5.1.2 NAD+
-
 Gluconobacter oxydans
6.5.1.2 NAD+
-
 Desulfovibrio vulgaris
6.5.1.2 NAD+
-
 Thermotoga maritima
6.5.1.2 NAD+
-
 Syntrophotalea carbinolica
6.5.1.2 NAD+
-
 Oleidesulfovibrio alaskensis
6.5.1.2 NAD+
-
 Synechococcus elongatus
6.5.1.2 NAD+
-
 Lawsonia intracellularis