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Literature summary extracted from

  • Dorighetto Cogo, A.J.; Dutra Ferreira, K.D.R.; Okorokov, L.A.; Ramos, A.C.; Facanha, A.R.; Okorokova-Facanha, A.L.
    Spermine modulates fungal morphogenesis and activates plasma membrane H+-ATPase during yeast to hyphae transition (2018), Biol. Open, 7, pii: bio029660 .
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
7.1.2.1 indole-3-acetic acid
-
Yarrowia lipolytica
7.1.2.1 spermine a concentration of 1 mM is the most effective Yarrowia lipolytica

Inhibitors

EC Number Inhibitors Comment Organism Structure
7.1.2.1 sodium orthovanadate specific inhibitor Yarrowia lipolytica

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
7.1.2.1 plasma membrane
-
Yarrowia lipolytica 5886
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7.1.2.1 ATP + H2O + H+[side 1] Yarrowia lipolytica
-
ADP + phosphate + H+[side 2]
-
?
7.1.2.1 ATP + H2O + H+[side 1] Yarrowia lipolytica JM12
-
ADP + phosphate + H+[side 2]
-
?

Organism

EC Number Organism UniProt Comment Textmining
7.1.2.1 Yarrowia lipolytica
-
-
-
7.1.2.1 Yarrowia lipolytica JM12
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.1.2.1 ATP + H2O + H+[side 1]
-
Yarrowia lipolytica ADP + phosphate + H+[side 2]
-
?
7.1.2.1 ATP + H2O + H+[side 1]
-
Yarrowia lipolytica JM12 ADP + phosphate + H+[side 2]
-
?

Synonyms

EC Number Synonyms Comment Organism
7.1.2.1 plasma membrane H+-ATPase
-
Yarrowia lipolytica
7.1.2.1 plasma membrane P-type H+-ATPase
-
Yarrowia lipolytica

General Information

EC Number General Information Comment Organism
7.1.2.1 physiological function the enzyme generates the electrochemical proton-motive force across the membrane that drives the energy-dependent uptake of amino acids, sugars, nucleosides, and inorganic ions. In addition, H+ transport mediated by this enzyme contributes to the regulation of intracellular pH and surface pH along the hyphae Yarrowia lipolytica