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Literature summary extracted from

  • Cao, Y.; Zhang, H.; Liu, H.; Liu, W.; Zhang, R.; Xian, M.; Liu, H.
    Biosynthesis and production of sabinene current state and perspectives (2018), Appl. Microbiol. Biotechnol., 102, 1535-1544 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.2.3.110 sequence comparisons and phylogenetic analysis Citrus unshiu
4.2.3.110 sequence comparisons and phylogenetic analysis Citrus jambhiri
4.2.3.110 sequence comparisons and phylogenetic analysis Salvia officinalis
4.2.3.110 sequence comparisons and phylogenetic analysis Picea sitchensis
4.2.3.110 sequence comparisons and phylogenetic analysis Salvia pomifera
4.2.3.110 sequence comparisons and phylogenetic analysis Thuja plicata
4.2.3.110 sequence comparisons and phylogenetic analysis Murraya koenigii
4.2.3.110 sequence comparisons and phylogenetic analysis Hedychium coronarium

Protein Variants

EC Number Protein Variants Comment Organism
4.2.3.110 additional information strategies in engineering sabinene production, overview Citrus unshiu
4.2.3.110 additional information strategies in engineering sabinene production, overview Citrus jambhiri
4.2.3.110 additional information strategies in engineering sabinene production, overview Salvia officinalis
4.2.3.110 additional information strategies in engineering sabinene production, overview Picea sitchensis
4.2.3.110 additional information strategies in engineering sabinene production, overview Thuja plicata
4.2.3.110 additional information strategies in engineering sabinene production, overview Murraya koenigii
4.2.3.110 additional information strategies in engineering sabinene production, overview Phomopsis sp. EC-4
4.2.3.110 additional information strategies in engineering sabinene production, overview. Biosynthetic pathway using both the non-mevalonate MEP and mevalonate MVA pathways combining the geranyl diphosphate synthase genes and sabinene synthase from Salvia pomifera, and engineering native Erg20p into a GPP synthase and heterologous expression of sabinene synthase from Salvia pomifera Salvia pomifera

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.2.3.110 chloroplast
-
 Picea sitchensis 9507
-
4.2.3.110 chloroplast
-
 Murraya koenigii 9507
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.2.3.110 geranyl diphosphate Citrus unshiu
-
 (+)-sabinene + diphosphate
-
 ?
4.2.3.110 geranyl diphosphate Citrus jambhiri
-
 (+)-sabinene + diphosphate
-
 ?
4.2.3.110 geranyl diphosphate Salvia officinalis
-
 (+)-sabinene + diphosphate
-
 ?
4.2.3.110 geranyl diphosphate Picea sitchensis
-
 (+)-sabinene + diphosphate
-
 ?
4.2.3.110 geranyl diphosphate Salvia pomifera
-
 (+)-sabinene + diphosphate
-
 ?
4.2.3.110 geranyl diphosphate Thuja plicata
-
 (+)-sabinene + diphosphate
-
 ?
4.2.3.110 geranyl diphosphate Murraya koenigii
-
 (+)-sabinene + diphosphate
-
 ?
4.2.3.110 geranyl diphosphate Phomopsis sp. EC-4
-
 (+)-sabinene + diphosphate
-
 ?
4.2.3.110 geranyl diphosphate Hedychium coronarium
-
 (+)-sabinene + diphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.2.3.110 Citrus jambhiri
-
-
-
4.2.3.110 Citrus unshiu
-
-
-
4.2.3.110 Hedychium coronarium
-
-
-
4.2.3.110 Murraya koenigii A0A1U9M7Y9
-
-
4.2.3.110 Phomopsis sp. EC-4
-
-
-
4.2.3.110 Picea sitchensis F1CKJ1
-
-
4.2.3.110 Salvia officinalis O81193
-
-
4.2.3.110 Salvia pomifera A6XH06
-
-
4.2.3.110 Thuja plicata R9WS05
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
4.2.3.110 geranyl diphosphate = (+)-sabinene + diphosphate proposed reaction mechanism of sabinene synthase via (3R)-3-linalyl diphosphate and (3R)-3-alpha-terpinyl cation Citrus unshiu
a
4.2.3.110 geranyl diphosphate = (+)-sabinene + diphosphate proposed reaction mechanism of sabinene synthase via (3R)-3-linalyl diphosphate and (3R)-3-alpha-terpinyl cation Citrus jambhiri
a
4.2.3.110 geranyl diphosphate = (+)-sabinene + diphosphate proposed reaction mechanism of sabinene synthase via (3R)-3-linalyl diphosphate and (3R)-3-alpha-terpinyl cation Salvia officinalis
a
4.2.3.110 geranyl diphosphate = (+)-sabinene + diphosphate proposed reaction mechanism of sabinene synthase via (3R)-3-linalyl diphosphate and (3R)-3-alpha-terpinyl cation Picea sitchensis
a
4.2.3.110 geranyl diphosphate = (+)-sabinene + diphosphate proposed reaction mechanism of sabinene synthase via (3R)-3-linalyl diphosphate and (3R)-3-alpha-terpinyl cation Salvia pomifera
a
4.2.3.110 geranyl diphosphate = (+)-sabinene + diphosphate proposed reaction mechanism of sabinene synthase via (3R)-3-linalyl diphosphate and (3R)-3-alpha-terpinyl cation Thuja plicata
a
4.2.3.110 geranyl diphosphate = (+)-sabinene + diphosphate proposed reaction mechanism of sabinene synthase via (3R)-3-linalyl diphosphate and (3R)-3-alpha-terpinyl cation Murraya koenigii
a
4.2.3.110 geranyl diphosphate = (+)-sabinene + diphosphate proposed reaction mechanism of sabinene synthase via (3R)-3-linalyl diphosphate and (3R)-3-alpha-terpinyl cation Hedychium coronarium
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.2.3.110 leaf
-
 Citrus unshiu
-
4.2.3.110 leaf
-
 Citrus jambhiri
-
4.2.3.110 leaf
-
 Salvia officinalis
-
4.2.3.110 leaf
-
 Picea sitchensis
-
4.2.3.110 leaf
-
 Salvia pomifera
-
4.2.3.110 leaf
-
 Thuja plicata
-
4.2.3.110 leaf
-
 Murraya koenigii
-
4.2.3.110 leaf
-
 Hedychium coronarium
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.3.110 geranyl diphosphate
-
 Citrus unshiu (+)-sabinene + diphosphate
-
 ?
4.2.3.110 geranyl diphosphate
-
 Citrus jambhiri (+)-sabinene + diphosphate
-
 ?
4.2.3.110 geranyl diphosphate
-
 Salvia officinalis (+)-sabinene + diphosphate
-
 ?
4.2.3.110 geranyl diphosphate
-
 Picea sitchensis (+)-sabinene + diphosphate
-
 ?
4.2.3.110 geranyl diphosphate
-
 Salvia pomifera (+)-sabinene + diphosphate
-
 ?
4.2.3.110 geranyl diphosphate
-
 Thuja plicata (+)-sabinene + diphosphate
-
 ?
4.2.3.110 geranyl diphosphate
-
 Murraya koenigii (+)-sabinene + diphosphate
-
 ?
4.2.3.110 geranyl diphosphate
-
 Phomopsis sp. EC-4 (+)-sabinene + diphosphate
-
 ?
4.2.3.110 geranyl diphosphate
-
 Hedychium coronarium (+)-sabinene + diphosphate
-
 ?
4.2.3.110 additional information the enzyme produces also (-)-sabinene Picea sitchensis ?
-
 ?
4.2.3.110 additional information the enzyme produces also (-)-sabinene Murraya koenigii ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.2.3.110 CjSabS2
-
 Citrus jambhiri
4.2.3.110 CuSabS2
-
 Citrus unshiu
4.2.3.110 HcSabS
-
 Hedychium coronarium
4.2.3.110 MkSabS
-
 Murraya koenigii
4.2.3.110 MKTPS1
-
 Murraya koenigii
4.2.3.110 MKTPS1
-
 Phomopsis sp. EC-4
4.2.3.110 PsSabS1
-
 Picea sitchensis
4.2.3.110 PsSabS2
-
 Picea sitchensis
4.2.3.110 SaBS
-
 Citrus unshiu
4.2.3.110 SaBS
-
 Citrus jambhiri
4.2.3.110 SaBS
-
 Salvia officinalis
4.2.3.110 SaBS
-
 Picea sitchensis
4.2.3.110 SaBS
-
 Salvia pomifera
4.2.3.110 SaBS
-
 Thuja plicata
4.2.3.110 SaBS
-
 Murraya koenigii
4.2.3.110 SaBS
-
 Hedychium coronarium
4.2.3.110 SoSabS2
-
 Salvia officinalis
4.2.3.110 SpSabS2
-
 Salvia pomifera
4.2.3.110 SSS
-
 Picea sitchensis
4.2.3.110 TPS-sab
-
 Picea sitchensis
4.2.3.110 TpSabS
-
 Thuja plicata

Expression

EC Number Organism Comment Expression
4.2.3.110 Hedychium coronarium strategies in engineering sabinene production, overview additional information

General Information

EC Number General Information Comment Organism
4.2.3.110 physiological function the endophytic fungus, Phomopsis sp. EC-4, shows the ability to emit sabinene as a primary component of its volatile organic compounds Phomopsis sp. EC-4