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Literature summary extracted from

  • Roether, W.; Austen, S.; Birke, J.; Jendrossek, D.
    Cleavage of rubber by the latex clearing protein (Lcp) of Streptomyces sp. strain K30 molecular insights (2016), Appl. Environ. Microbiol., 82, 6593-6602 .
    View publication on PubMedView publication on EuropePMC

Protein Variants

EC Number Protein Variants Comment Organism
1.13.11.87 H198A mutant protein is stable, contains no heme group and is inactive Streptomyces sp. K30
1.13.11.87 H203A mutant enzyme reveals wild-type properties Streptomyces sp. K30
1.13.11.87 H232A mutant enzyme reveals wild-type properties Streptomyces sp. K30
1.13.11.87 H259A mutant enzyme reveals wild-type properties Streptomyces sp. K30
1.13.11.87 H266A mutant enzyme reveals wild-type properties Streptomyces sp. K30
1.13.11.87 R164A mutant protein is stable and contains a heme group but is inactive Streptomyces sp. K30
1.13.11.87 R195A mutant enzyme is colorless and instable Streptomyces sp. K30
1.13.11.87 R202A mutant enzyme is colorless and instable Streptomyces sp. K30
1.13.11.87 T168A mutant protein is stable and contains a heme group but is inactive Streptomyces sp. K30

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.13.11.87 extracellular
-
 Streptomyces sp. K30
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.13.11.87 cis-1,4-polyisoprene + O2 Streptomyces sp. K30
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.13.11.87 Streptomyces sp. K30 Q3L8N0
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.11.87 cis-1,4-polyisoprene + O2
-
 Streptomyces sp. K30 ?
-
 ?
1.13.11.87 cis-1,4-polyisoprene + O2 the three DUF2236 domain-specific residues (R164, T168, and H198) and two conserved arginines (R195 and R202) are essential for activity, stability, and/or incorporation of the heme cofactor in the enzyme Streptomyces sp. K30 ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.13.11.87 latex clearing protein
-
 Streptomyces sp. K30
1.13.11.87 Lcp
-
 Streptomyces sp. K30

Cofactor

EC Number Cofactor Comment Organism Structure
1.13.11.87 heme heme b cytochrome Streptomyces sp. K30