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Literature summary extracted from

  • Kaster, A.; Moll, J.; Parey, K.; Thauer, R.
    Coupling of ferredoxin and heterodisulfide reduction via electron bifurcation in hydrogenotrophic methanogenic archaea (2011), Proc. Natl. Acad. Sci. USA, 108, 2981-2986 .
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.8.98.5 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + H+ Methanothermobacter marburgensis
-
 H2 + oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB
-
 ?
1.8.98.5 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + H+ Methanothermobacter marburgensis DSM 2133
-
 H2 + oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.8.98.5 Methanothermobacter marburgensis
-
-
-
1.8.98.5 Methanothermobacter marburgensis DSM 2133
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.8.98.5 DEAE-Sepharose column chromatography, Q-Sepharose column chromatography, and Superdex 200 gel filtration Methanothermobacter marburgensis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.98.5 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + H+
-
 Methanothermobacter marburgensis H2 + oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB
-
 ?
1.8.98.5 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + H+
-
 Methanothermobacter marburgensis DSM 2133 H2 + oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB
-
 ?
1.8.98.5 reduced metronidazole + CoB + CoM + H+
-
 Methanothermobacter marburgensis H2 + oxidized metronidazole + CoM-S-S-CoB
-
 ?
1.8.98.5 reduced metronidazole + CoB + CoM + H+
-
 Methanothermobacter marburgensis DSM 2133 H2 + oxidized metronidazole + CoM-S-S-CoB
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.8.98.5 MvhADG/HdrABC
-
 Methanothermobacter marburgensis

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.8.98.5 70
-
-
 Methanothermobacter marburgensis

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.8.98.5 7.5
-
-
 Methanothermobacter marburgensis

Cofactor

EC Number Cofactor Comment Organism Structure
1.8.98.5 [4Fe-4S]-center
-
 Methanothermobacter marburgensis