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Literature summary extracted from

  • Vavricka, C.; Han, Q.; Huang, Y.; Erickson, S.M.; Harich, K.; Christensen, B.M.; Li, J.
    From L-Dopa to dihydroxyphenylacetaldehyde a toxic biochemical pathway plays a vital physiological function in insects (2011), PLoS ONE, 6, e16124 .
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.107 L-Dopa + O2 + H2O Drosophila melanogaster
-
 3,4-dihydroxyphenylacetaldehyde + CO2 + NH3 + H2O2
-
 ?
4.1.1.107 L-Dopa + O2 + H2O Culex quinquefasciatus
-
 3,4-dihydroxyphenylacetaldehyde + CO2 + NH3 + H2O2
-
 ?
4.1.1.107 L-Dopa + O2 + H2O Anopheles gambiae
-
 3,4-dihydroxyphenylacetaldehyde + CO2 + NH3 + H2O2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.107 Anopheles gambiae
-
-
-
4.1.1.107 Culex quinquefasciatus
-
-
-
4.1.1.107 Drosophila melanogaster
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.107 alpha-methyl-L-Dopa + O2 + H2O 10-12% activity compared to L-Dopa Drosophila melanogaster 3,4-dihydroxyphenylacetone + CO2 + NH3 + H2O2
-
 ?
4.1.1.107 alpha-methyl-L-Dopa + O2 + H2O 10-12% activity compared to L-Dopa Culex quinquefasciatus 3,4-dihydroxyphenylacetone + CO2 + NH3 + H2O2
-
 ?
4.1.1.107 alpha-methyl-L-Dopa + O2 + H2O 10-12% activity compared to L-Dopa Anopheles gambiae 3,4-dihydroxyphenylacetone + CO2 + NH3 + H2O2
-
 ?
4.1.1.107 L-Dopa + O2 + H2O
-
 Drosophila melanogaster 3,4-dihydroxyphenylacetaldehyde + CO2 + NH3 + H2O2
-
 ?
4.1.1.107 L-Dopa + O2 + H2O
-
 Culex quinquefasciatus 3,4-dihydroxyphenylacetaldehyde + CO2 + NH3 + H2O2
-
 ?
4.1.1.107 L-Dopa + O2 + H2O
-
 Anopheles gambiae 3,4-dihydroxyphenylacetaldehyde + CO2 + NH3 + H2O2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.1.1.107 DHPAA synthase
-
 Drosophila melanogaster
4.1.1.107 DHPAA synthase
-
 Culex quinquefasciatus
4.1.1.107 DHPAA synthase
-
 Anopheles gambiae
4.1.1.107 EAT37246
-
 Drosophila melanogaster
4.1.1.107 EAT37246
-
 Culex quinquefasciatus
4.1.1.107 EAT37246
-
 Anopheles gambiae

Cofactor

EC Number Cofactor Comment Organism Structure
4.1.1.107 pyridoxal 5'-phosphate
-
 Drosophila melanogaster
4.1.1.107 pyridoxal 5'-phosphate
-
 Culex quinquefasciatus
4.1.1.107 pyridoxal 5'-phosphate
-
 Anopheles gambiae

General Information

EC Number General Information Comment Organism
4.1.1.107 physiological function the enzyme plays a role in the formation of colorless, flexible cuticle Drosophila melanogaster
4.1.1.107 physiological function the enzyme plays a role in the formation of colorless, flexible cuticle Culex quinquefasciatus
4.1.1.107 physiological function the enzyme plays a role in the formation of colorless, flexible cuticle Anopheles gambiae