Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Aughey, G.; Grice, S.; Liu, J.
    The Interplay between Myc and CTP synthase in Drosophila (2016), PLoS Genet., 12, e1005867 .
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
6.3.4.2 Drosophila melanogaster X2JCY2
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.3.4.2 ovarian follicle Myc protein levels correlate with cytoophidium abundance in follicle epithelia Drosophila melanogaster
-

General Information

EC Number General Information Comment Organism
6.3.4.2 physiological function Myc protein levels correlate with cytoophidium abundance in follicle epithelia. Reducing Myc levels results in cytoophidium loss and small nuclear size in follicle cells, while overexpression of Myc increases the length of cytoophidia and the nuclear size of follicle cells. Ectopic expression of Myc induces cytoophidium formation in late stage follicle cells. Furthermore, knock-down of CTPsyn is sufficient to suppress the overgrowth phenotype induced by Myc overexpression Drosophila melanogaster