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Literature summary extracted from

  • Jung, W.; Yu, O.; Lau, S.M.; OKeefe, D.P.; Odell, J.; Fader, G.; McGonigle, B.
    Identification and expression of isoflavone synthase, the key enzyme for biosynthesis of isoflavones in legumes (2000), Nat. Biotechnol., 18, 208-212 .
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.87 Glycine max O48926
-
-
1.14.14.87 Glycine max Q9M6B9
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.87 (2S)-naringenin + O2 + [reduced NADPH-hemoprotein reductase]
-
 Glycine max 2,4',5,7-tetrahydroxyisoflavanone + H2O + [oxidized NADPH-hemoprotein reductase]
-
 ?
1.14.14.87 liquiritigenin + O2 + [reduced NADPH-hemoprotein reductase]
-
 Glycine max 2,4',7-trihydroxyisoflavanone + H2O + [oxidized NADPH-hemoprotein reductase]
-
 ?
1.14.14.87 additional information the amount of conversion of naringenin to genistein is about 50% less than the conversion of liquiritigenin to daidzein for both isoforms IFS1 and IFS2 Glycine max ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.14.87 Cyp93C1
-
 Glycine max
1.14.14.87 IFS1
-
 Glycine max
1.14.14.87 IFS2
-
 Glycine max

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.14.87 cytochrome P450
-
 Glycine max

General Information

EC Number General Information Comment Organism
1.14.14.87 physiological function expression in Arabidopsis thaliana leads to production of the isoflavone genistein Glycine max