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Literature summary extracted from

  • Schlicke, H.; Hartwig, A.S.; Firtzlaff, V.; Richter, A.S.; Glaesser, C.; Maier, K.; Finkemeier, I.; Grimm, B.
    Induced deactivation of genes encoding chlorophyll biosynthesis enzymes disentangles tetrapyrrole-mediated retrograde signaling (2014), Mol. Plant, 7, 1211-1227 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.13.81 gene CHL27, encoding the CHLH subunit of enzyme Mg protoporphyrin monomethylester cyclase Arabidopsis thaliana

Protein Variants

EC Number Protein Variants Comment Organism
1.14.13.81 additional information silencing of gene CHL27 by siRNA overexpression, encoding the CHLH subunit of enzyme Mg protoporphyrin monomethylester cyclase, for more than 24 h results in necrotic leaf lesions and modulated transcript levels of oxidative stress-responsive and photosynthesis-associated nuclear genes (PhANGs), transcriptome analysis, phenotypes, overview Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.13.81 magnesium-protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2 Arabidopsis thaliana
-
 3,8-divinyl protochlorophyllide a + 3 NADP+ + 5 H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.13.81 Arabidopsis thaliana Q9M591
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.13.81 seedling
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.13.81 magnesium-protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2
-
 Arabidopsis thaliana 3,8-divinyl protochlorophyllide a + 3 NADP+ + 5 H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.13.81 Mg protoporphyrin monomethylester cyclase
-
 Arabidopsis thaliana
1.14.13.81 MgPME oxidative cyclase
-
 Arabidopsis thaliana

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.13.81 NADPH
-
 Arabidopsis thaliana

General Information

EC Number General Information Comment Organism
1.14.13.81 malfunction decreased CHL27 transcript levels result in a substantial reduction of activity of MgPME cyclase and MgP monomethylester accumulation, in comparison to dexamethasone-treated wild-type seedlings Arabidopsis thaliana