Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Lazar, N.; Fay, A.; Nandakumar, M.; Boyle, K.E.; Xavier, J.; Rhee, K.; Glickman, M.S.
    Control of biotin biosynthesis in mycobacteria by a pyruvate carboxylase dependent metabolic signal (2017), Mol. Microbiol., 106, 1018-1031 .
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
6.4.1.1 Mycolicibacterium smegmatis A0QV14
-
-
6.4.1.1 Mycolicibacterium smegmatis ATCC 700084 A0QV14
-
-

Synonyms

EC Number Synonyms Comment Organism
6.4.1.1 MSmeg_2412
-
 Mycolicibacterium smegmatis
6.4.1.1 PYC
-
 Mycolicibacterium smegmatis

General Information

EC Number General Information Comment Organism
6.4.1.1 physiological function a gene disruption strain is auxotrohp for biotin due to failure to transcriptionally induce late stage biotin biosynthetic genes in low biotin conditions. Catalytically active Pyc is required and can be supported by Mycobacterium tuberculosis Pyc Mycolicibacterium smegmatis